Fluticasone propionate
- Generic Name
- Fluticasone propionate
- Brand Names
- Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
- Drug Type
- Small Molecule
- Chemical Formula
- C25H31F3O5S
- CAS Number
- 80474-14-2
- Unique Ingredient Identifier
- O2GMZ0LF5W
- Background
Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.
- Indication
Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.
- Associated Conditions
- Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
- Associated Therapies
- -
Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents
- Conditions
- Interventions
- First Posted Date
- 2010-07-12
- Last Posted Date
- 2017-11-09
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 350
- Registration Number
- NCT01159912
- Locations
- 🇷🇴
GSK Investigational Site, Iasi, Romania
Real-world Effectiveness and Cost-effectiveness of Leading Inhaled Corticosteroids in Asthma Management
- First Posted Date
- 2010-06-10
- Last Posted Date
- 2013-03-14
- Lead Sponsor
- Research in Real-Life Ltd
- Target Recruit Count
- 815377
- Registration Number
- NCT01141439
- Locations
- 🇬🇧
General Practice Research Database, London, United Kingdom
Vitamin D Plus Fluticasone Propionate
- Conditions
- Interventions
- First Posted Date
- 2010-04-15
- Last Posted Date
- 2014-10-09
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 35
- Registration Number
- NCT01103934
- Locations
- 🇺🇸
The University of Chicago, Chicago, Illinois, United States
BI 671800 ED in Steroid-naive Asthmatic Patients
- Conditions
- Interventions
- First Posted Date
- 2010-03-24
- Last Posted Date
- 2022-05-31
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 389
- Registration Number
- NCT01092143
- Locations
- 🇨🇦
1268.17.02003 Boehringer Ingelheim Investigational Site, Toronto, Ontario, Canada
🇺🇸1268.17.01034 Boehringer Ingelheim Investigational Site, Baltimore, Maryland, United States
🇺🇸1268.17.01027 Boehringer Ingelheim Investigational Site, Novi, Michigan, United States
A Study To Explore The Effect On Inflammatory Markers After Nasal Allergen Challenge In Subjects With Seasonal Allergic Rhinitis And The Effect Of A Single Dose Of Ibuprofen Or Fluticasone Propionate On The Allergen Response.
- Conditions
- Interventions
- First Posted Date
- 2010-02-08
- Last Posted Date
- 2010-06-02
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 18
- Registration Number
- NCT01064726
- Locations
- 🇺🇸
Pfizer Investigational Site, Omaha, Nebraska, United States
Fluticasone Furoate/GW642444 Inhalation Powder Long-Term Safety Study
- Conditions
- Interventions
- First Posted Date
- 2009-11-23
- Last Posted Date
- 2018-02-15
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 503
- Registration Number
- NCT01018186
- Locations
- 🇺🇦
GSK Investigational Site, Simferopol, Ukraine
A Proof of Concept Study to Evaluate the Dose Response for the Systemic Benefit Risk Ratio of Inhaled Fluticasone Propionate in Chronic Obstructive Pulmonary Disease
- First Posted Date
- 2009-10-15
- Last Posted Date
- 2023-05-19
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 18
- Registration Number
- NCT00995475
Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma
- First Posted Date
- 2009-10-15
- Last Posted Date
- 2019-04-12
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 21
- Registration Number
- NCT00995657
- Locations
- 🇬🇧
Asthma and Allergy Research Group, University of Dundee, Dundee, Tayside, United Kingdom
Inhaled Corticosteroid Withdrawal in Patients With Chronic Obstructive Pulmonary Disease
- First Posted Date
- 2009-09-11
- Last Posted Date
- 2015-02-10
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 2488
- Registration Number
- NCT00975195
- Locations
- 🇭🇺
352.2046.36004 Boehringer Ingelheim Investigational Site, Komarom, Hungary
🇭🇺352.2046.36001 Boehringer Ingelheim Investigational Site, Szarvas, Hungary
🇭🇺352.2046.36006 Boehringer Ingelheim Investigational Site, Pecs, Hungary
Safety, Tolerability and Pharmacokinetics of Multiple Doses of VAK694 in Atopic Subjects With Seasonal Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2009-06-30
- Last Posted Date
- 2020-12-19
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 35
- Registration Number
- NCT00929968
- Locations
- 🇺🇸
Altoona Center for Clinical Research, Duncansville, Pennsylvania, United States
🇨🇦Novartis Investigative Site, Ottawa, Ontario, Canada
Drug Development Updates
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