Ibuprofen

Generic Name
Ibuprofen
Brand Names
Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
Drug Type
Small Molecule
Chemical Formula
C13H18O2
CAS Number
15687-27-1
Unique Ingredient Identifier
WK2XYI10QM
Background

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication

Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions
Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
Associated Therapies
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Treatment of Fever Due to Malaria With Ibuprofen

Phase 4
Completed
Conditions
First Posted Date
2005-09-14
Last Posted Date
2005-09-21
Lead Sponsor
Albert Schweitzer Hospital
Target Recruit Count
50
Registration Number
NCT00167713
Locations
🇬🇦

Medical research Unit, Lambaréné, Lambaréné, Moyen Ogooué, Gabon

Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen

First Posted Date
2005-09-05
Last Posted Date
2006-11-29
Lead Sponsor
The George Institute
Target Recruit Count
1000
Registration Number
NCT00145730

Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease

First Posted Date
2005-06-22
Last Posted Date
2020-10-08
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Target Recruit Count
10
Registration Number
NCT00115336
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

Pain Relief - Tramadol Versus Ibuprofen

First Posted Date
2005-05-17
Last Posted Date
2005-11-10
Lead Sponsor
Royal Liverpool University Hospital
Target Recruit Count
40
Registration Number
NCT00111046
Locations
🇬🇧

Royal Liverpool University Hospital, Liverpool, Merseyside, United Kingdom

The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease

Phase 4
Completed
Conditions
First Posted Date
2002-09-27
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
50
Registration Number
NCT00046358
Locations
🇺🇸

National Institute of Mental Health (NIMH), Bethesda, Maryland, United States

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
University of Pittsburgh
Registration Number
NCT00002276
Locations
🇺🇸

Hemophilia Ctr of Western PA / Univ of Pittsburgh, Pittsburgh, Pennsylvania, United States

Ibuprofen in Sepsis Study

First Posted Date
1999-10-28
Last Posted Date
2016-02-01
Lead Sponsor
Vanderbilt University
Registration Number
NCT00000574

Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis

Not Applicable
Completed
Conditions
First Posted Date
1999-10-19
Last Posted Date
2015-03-25
Lead Sponsor
FDA Office of Orphan Products Development
Target Recruit Count
75
Registration Number
NCT00004440
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