Pyridoxal phosphate
- Generic Name
- Pyridoxal phosphate
- Brand Names
- EnBrace HR, EnLyte
- Drug Type
- Small Molecule
- Chemical Formula
- C8H10NO6P
- CAS Number
- 54-47-7
- Unique Ingredient Identifier
- F06SGE49M6
- Background
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
- Indication
For nutritional supplementation and for treating dietary shortage or imbalance.
- Associated Conditions
- Anemia, Pernicious, Vitamin B6 Deficiency
- Associated Therapies
- Folate supplementation therapy, Vitamin supplementation
Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency
- Conditions
- Interventions
- First Posted Date
- 2021-01-12
- Last Posted Date
- 2024-02-26
- Lead Sponsor
- Medicure
- Target Recruit Count
- 15
- Registration Number
- NCT04706013
- Locations
- 🇺🇸
Duke Children's Hospital, Durham, North Carolina, United States
🇺🇸Akron's Children's Hospital, Akron, Ohio, United States
🇦🇺Queensland Children's Hospital, South Brisbane, Queensland, Australia
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
- First Posted Date
- 2018-11-13
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Colorado State University
- Target Recruit Count
- 9
- Registration Number
- NCT03738943
- Locations
- 🇺🇸
Human Performance and Clinical Research Laboratory, Fort Collins, Colorado, United States
Safety and Efficacy of Pyridoxal 5' -Phosphate in the Treatment of Tardive Dyskinesia
- First Posted Date
- 2009-06-10
- Last Posted Date
- 2019-02-15
- Lead Sponsor
- Medicure
- Target Recruit Count
- 53
- Registration Number
- NCT00917293
- Locations
- 🇨🇦
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
🇨🇦Windsor Regional Hospital, Windsor, Ontario, Canada
🇨🇦Vancouver Island Health Authority, Victoria, British Columbia, Canada
Drug Development Updates
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