Lidocaine

Generic Name: Lidocaine

Brand Names: Agoneaze, Akten, Alivio, Anestacon, Anodyne Lpt, Astero, Band-aid Hurt-free, Cathejell, Curacaine, Depo-medrol With Lidocaine, Dermacinrx Lido V Pak, Dermacinrx Phn Pak, Dermacinrx Prikaan, Diphen, Emla, Fortacin, Glydo, Instillagel, Kenalog, Lido Bdk, Lido-prilo Caine Pack, Lidocan, Lidodan, Lidoderm, Lidopac, Lidopril, Lidopro, Lidosol, Lidothol, Lidotral, Lignospan, Marcaine, Max-freeze, Medi-derm With Lidocaine, Neo-bex, Octocaine, Octocaine With Epinephrine, Oraqix, P-care, P-care X, Pliaglis, Prilolid, Prizotral, Procomycin, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Relador, Synera, Triple Antibiotic, Venipuncture Px1, Viadur, Xylocaine, Xylocaine With Epinephrine, Xylocard, Xylonor, Zingo, Ztlido

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₂₂N_₂O

CAS Number: 137-58-6

Unique Ingredient Identifier: 98PI200987

Background: Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical p...

Indication: Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks .

Associated Conditions: Acute Otitis Media (AOM), Anorectal discomfort, Arrhythmia, Back Pain Lower Back, Bacterial Vaginosis (BV), Burns, Cervical Syndrome, Earache, Fissure;Anal, Haemorrhoids, Infection, Inflammatory Reaction caused by ear infection-not otherwise specified, Insect Bites, Joint Pain, Mixed Vaginal Infections, Multiple Myeloma (MM), Myringitis, Neuritis, Osteolysis caused by Bone Tumors, Osteoporosis, Otitis Externa, Pain caused by ear infection-not otherwise specified, Pain, Inflammatory, Postherpetic Neuralgia, Primary Hyperparathyroidism (PHPT), Rheumatic Diseases, Rheumatic Joint Disease, Sciatica, Skin Irritation, Soft Tissue Inflammation, Sore Throat, Sunburn, Susceptible infections, Trichomonas Vaginitis, Ulcers, Leg, Urethral Strictures, Ventricular Arrhythmia, Vulvovaginal Candidiasis, Abrasions, Anal discomfort, Cutaneous lesions, Gum pain, Minor burns, Superficial Wounds, Susceptible Bacterial Infections, Ulceration of the mouth, Viral infections of the external ear canal

Associated Therapies: Local Anaesthesia therapy, Post Myocardial Infarction Treatment, Regional Anesthesia therapy

Clinical Trials

Intravenous Lidocaine for Laparoscopic Cholecystectomy

Not Applicable

Completed

Conditions: Postoperative Pain
Opioid Consumption

Interventions: Drug: Fentanyl
Drug: Lidocaine

First Posted Date: 2010-02-04

Last Posted Date: 2011-01-13

Lead Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Target Recruit Count: 80

Registration Number: NCT01062906

Locations: 🇨🇦
McGill University Health Centre, Montreal General Hospital, Montreal, Quebec, Canada

Bupivacaine Versus Lidocaine on Inflammatory Regulation

Phase 4

Completed

Conditions: Pain

Interventions: Drug: Bupivacaine
Drug: Lidocaine

First Posted Date: 2010-02-02

Last Posted Date: 2018-05-31

Lead Sponsor: University of Maryland

Target Recruit Count: 11

Registration Number: NCT01060774

Locations: 🇺🇸
University of Maryland, Baltimore College of Dental Surgery, Baltimore, Maryland, United States

Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint

Phase 4

Terminated

Conditions: Arthritis Multiple Joint

Interventions: Drug: Steroid - Triamcinolone Acetonide
Drug: Lidocaine
Drug: Botulinum Toxin Type A

First Posted Date: 2010-01-11

Last Posted Date: 2017-10-06

Lead Sponsor: University of Missouri-Columbia

Target Recruit Count: 8

Registration Number: NCT01045694

Locations: 🇺🇸
University of Missouri, Columbia, Missouri, United States

Efficacy of Remifentanil Compared to Lidocaine on the Incidence of Coughing During Emergence of Anesthesia

Not Applicable

Completed

Conditions: Cough
Anesthesia
Extubation

Interventions: Drug: Remifentanil
Drug: lidocaine

First Posted Date: 2009-12-04

Last Posted Date: 2010-07-14

Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Target Recruit Count: 93

Registration Number: NCT01026129

Locations: 🇨🇦
Centre Hospitalier de l'Université de Montréal-Hôpital Notre-Dame, Montreal, Quebec, Canada

Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided Techniques

Phase 4

Terminated

Conditions: Face Pain

Interventions: Drug: chemodenervation
Drug: lidocaine

First Posted Date: 2009-10-09

Last Posted Date: 2016-12-29

Lead Sponsor: University of California, Los Angeles

Target Recruit Count: 17

Registration Number: NCT00992108

Locations: 🇺🇸
Westwood Associates, Los Angeles, California, United States

Lidocaine on Manifestations of Fibromyalgia

Phase 1

Completed

Conditions: Fibromyalgia
Chronic Pain

Interventions: Drug: Lidocaine

First Posted Date: 2009-10-08

Last Posted Date: 2009-10-09

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 30

Registration Number: NCT00991848

Locations: 🇧🇷
Federal University of São Paulo, São Paulo, Brazil

Intravenous Lidocaine for Fibromyalgia

Not Applicable

Completed

Conditions: Fibromyalgia

Interventions: Drug: Lidocaine

First Posted Date: 2009-09-30

Last Posted Date: 2009-09-30

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 30

Registration Number: NCT00986505

Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous Lidocaine

Not Applicable

Completed

Conditions: Colon Cancer
Inflammatory Bowel Diseases
Diverticulitis

Interventions: Procedure: Epidural Block
Drug: PCA Morphine
Drug: Lidocaine

First Posted Date: 2009-09-23

Last Posted Date: 2011-11-28

Lead Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Target Recruit Count: 60

Registration Number: NCT00982618

Locations: 🇨🇦
Montreal General Hospital, Montreal, Quebec, Canada

Effect of Lidocaine in Antiarrhythmic Dosage on Postoperative Cognitive Dysfunction in Supratentorial Craniotomy Dysfunction in Supratentorial Craniotomy

Phase 2

Completed

Conditions: Supratentorial Craniotomy Dysfunction

Interventions: Drug: saline
Drug: lidocaine

First Posted Date: 2009-09-14

Last Posted Date: 2013-05-22

Lead Sponsor: Capital Medical University

Target Recruit Count: 100

Registration Number: NCT00975910

Locations: 🇨🇳
Department of Anesthesiology,Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

Intraoperative Intravenous Lidocaine

Not Applicable

Completed

Conditions: Pain Intensity

Interventions: Drug: Lidocaine

First Posted Date: 2009-08-26

Last Posted Date: 2009-08-26

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 40

Registration Number: NCT00965796

Locations: 🇧🇷
Rioko K Sakata- Universidade Federal de São Paulo, São Paulo, Rua Botucatu-593, Brazil
🇧🇷
Universidade Federal de São Paulo, São Paulo, Brazil

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