Lidocaine

Generic Name: Lidocaine

Brand Names: Agoneaze, Akten, Alivio, Anestacon, Anodyne Lpt, Astero, Band-aid Hurt-free, Cathejell, Curacaine, Depo-medrol With Lidocaine, Dermacinrx Lido V Pak, Dermacinrx Phn Pak, Dermacinrx Prikaan, Diphen, Emla, Fortacin, Glydo, Instillagel, Kenalog, Lido Bdk, Lido-prilo Caine Pack, Lidocan, Lidodan, Lidoderm, Lidopac, Lidopril, Lidopro, Lidosol, Lidothol, Lidotral, Lignospan, Marcaine, Max-freeze, Medi-derm With Lidocaine, Neo-bex, Octocaine, Octocaine With Epinephrine, Oraqix, P-care, P-care X, Pliaglis, Prilolid, Prizotral, Procomycin, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Relador, Synera, Triple Antibiotic, Venipuncture Px1, Viadur, Xylocaine, Xylocaine With Epinephrine, Xylocard, Xylonor, Zingo, Ztlido

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₂₂N_₂O

CAS Number: 137-58-6

Unique Ingredient Identifier: 98PI200987

Background: Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical p...

Indication: Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks .

Associated Conditions: Acute Otitis Media (AOM), Anorectal discomfort, Arrhythmia, Back Pain Lower Back, Bacterial Vaginosis (BV), Burns, Cervical Syndrome, Earache, Fissure;Anal, Haemorrhoids, Infection, Inflammatory Reaction caused by ear infection-not otherwise specified, Insect Bites, Joint Pain, Mixed Vaginal Infections, Multiple Myeloma (MM), Myringitis, Neuritis, Osteolysis caused by Bone Tumors, Osteoporosis, Otitis Externa, Pain caused by ear infection-not otherwise specified, Pain, Inflammatory, Postherpetic Neuralgia, Primary Hyperparathyroidism (PHPT), Rheumatic Diseases, Rheumatic Joint Disease, Sciatica, Skin Irritation, Soft Tissue Inflammation, Sore Throat, Sunburn, Susceptible infections, Trichomonas Vaginitis, Ulcers, Leg, Urethral Strictures, Ventricular Arrhythmia, Vulvovaginal Candidiasis, Abrasions, Anal discomfort, Cutaneous lesions, Gum pain, Minor burns, Superficial Wounds, Susceptible Bacterial Infections, Ulceration of the mouth, Viral infections of the external ear canal

Associated Therapies: Local Anaesthesia therapy, Post Myocardial Infarction Treatment, Regional Anesthesia therapy

Clinical Trials

Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia

Not Applicable

Completed

Conditions: Anesthesia

Interventions: Drug: lidocaine

First Posted Date: 2008-01-15

Last Posted Date: 2023-11-29

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 149

Registration Number: NCT00594542

Safety and Efficacy of Lidocaine Infiltration in Suction Assisted Lipectomy

Phase 3

Conditions: Healthy

Interventions: Drug: Lidocaine

First Posted Date: 2008-01-11

Last Posted Date: 2008-01-11

Lead Sponsor: Hospital Militar de Santiago

Target Recruit Count: 60

Registration Number: NCT00591487

Locations: 🇨🇱
Hospital Militar de Santiago, Santiago, RM, Chile

Safety and Efficacy of Two Vaginal Products Versus Placebo in Patients With Vaginal Discomfort

Phase 2

Completed

Conditions: Vulvodynia

Interventions: Drug: placebo
Drug: lidocaine
Drug: Lidocaine/Diphenhydramine

First Posted Date: 2008-01-10

Last Posted Date: 2012-03-02

Lead Sponsor: Lumara Health, Inc.

Target Recruit Count: 105

Registration Number: NCT00590590

Locations: 🇺🇸
Advanced Clinical Research, Medford, Oregon, United States
🇺🇸
Lehigh Valley Health Network, Allentown, Pennsylvania, United States
🇺🇸
Woman's Hospital of Texas, Houston, Texas, United States

and more 45 locations

Epidural Clonidine for Lumbosacral Radiculopathy

Not Applicable

Terminated

Conditions: Lumbar and Other Intervertebral Disc Disorders With Radiculopathy

Interventions: Drug: Clonidine
Drug: Triamcinolone hexacetonide
Drug: Lidocaine HCl

First Posted Date: 2008-01-08

Last Posted Date: 2012-01-11

Lead Sponsor: Mayo Clinic

Target Recruit Count: 26

Registration Number: NCT00588354

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

Amiodarone for the Prevention of Reperfusion Ventricular Fibrillation

Not Applicable

Completed

Conditions: Other Intraoperative Cardiac Functional Disturbances During Cardiac Surgery

Interventions: Drug: Lidocaine
Drug: Amiodarone
Drug: Placebo

First Posted Date: 2008-01-07

Last Posted Date: 2011-08-11

Lead Sponsor: Mayo Clinic

Target Recruit Count: 342

Registration Number: NCT00587483

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

Local Anaesthetic for Transvaginal Egg Collection in IVF

Not Applicable

Completed

Conditions: Infertility

Interventions: Drug: lignocaine
Drug: normal saline

First Posted Date: 2007-11-06

Last Posted Date: 2007-11-06

Lead Sponsor: The Fertility Centre, New Zealand

Target Recruit Count: 75

Registration Number: NCT00554424

Locations: 🇳🇿
The Fertility Centre, Christchurch, Canterbury, New Zealand

Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction

Phase 1

Completed

Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Lung Cancer

Interventions: Drug: indocyanine green
Drug: lidocaine
Drug: vinorelbine ditartrate
Other: high performance liquid chromatography
Other: intracellular fluorescence polarization analysis
Other: liquid chromatography
Other: mass spectrometry
Other: pharmacological study

First Posted Date: 2007-10-08

Last Posted Date: 2019-03-11

Lead Sponsor: City of Hope Medical Center

Target Recruit Count: 47

Registration Number: NCT00540982

Locations: 🇺🇸
City of Hope Medical Group, Pasadena, California, United States
🇺🇸
City of Hope Comprehensive Cancer Center, Duarte, California, United States