Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 48
- Registration Number
- NCT00000826
- Locations
- 🇺🇸
University of Washington AIDS CRS, Seattle, Washington, United States
🇺🇸Ucsf Aids Crs, San Francisco, California, United States
A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Registration Number
- NCT00002294
- Locations
- 🇺🇸
UCI Med Ctr, Orange, California, United States
🇺🇸Dr Robert Larsen, Los Angeles, California, United States
🇺🇸UCSD, San Diego, California, United States
Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 500
- Registration Number
- NCT00000676
- Locations
- 🇺🇸
Northwestern University CRS, Chicago, Illinois, United States
🇺🇸Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States
🇺🇸Bmc Actg Crs, Boston, Massachusetts, United States
A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Registration Number
- NCT00002325
- Locations
- 🇺🇸
Tucson Veterans Administration Med Ctr, Tucson, Arizona, United States
🇺🇸McDowell Clinic, Phoenix, Arizona, United States
🇺🇸Dr Lawrence Cone, Rancho Mirage, California, United States
Dexamethasone in Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-28
- Target Recruit Count
- 36
- Registration Number
- NCT00000776
- Locations
- 🇺🇸
Northwestern Univ Med School, Chicago, Illinois, United States
🇺🇸Cook County Hosp, Chicago, Illinois, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Registration Number
- NCT00002040
- Locations
- 🇺🇸
Cook County Hosp, Chicago, Illinois, United States
🇺🇸Summitt Med Ctr / San Francisco Gen Hosp, Oakland, California, United States
🇺🇸Cornell Univ Med Ctr, New York, New York, United States
Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2009-06-03
- Lead Sponsor
- InterMune
- Target Recruit Count
- 60
- Registration Number
- NCT00012467
- Locations
- 🇺🇸
Houston Veterans Administration Med Ctr, Houston, Texas, United States
🇺🇸Univ of Texas / Med School at Houston, Houston, Texas, United States
🇵🇪Instituto de Medicina Tropical, Lima, Peru
Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2006-06-09
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 78
- Registration Number
- NCT00004808
Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2006-06-09
- Target Recruit Count
- 30
- Registration Number
- NCT00004938
Drug Development Updates
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