MedPath

Endostatin

Generic Name
Endostatin
Drug Type
Biotech
CAS Number
187888-07-9
Unique Ingredient Identifier
67RHC0R671
Indication

Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.

Local Injection and Systemic Therapy in the Treatment of NSCLC.

Phase 2
Not yet recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-09-30
Last Posted Date
2024-09-30
Lead Sponsor
Henan Cancer Hospital
Target Recruit Count
84
Registration Number
NCT06618391

Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma

Phase 1
Recruiting
Conditions
Osteosarcoma
Bone Cancer
Interventions
First Posted Date
2024-08-20
Last Posted Date
2025-04-30
Lead Sponsor
Shanghai 6th People's Hospital
Target Recruit Count
10
Registration Number
NCT06562673
Locations
🇨🇳

Shanghai Jiao Tong University School of Medicine, Shanghai Sixth People's Hospital,, Shanghai, China

Recombinant Human Endostatin Combined With Envafolimab and Synchronal Radiochemotherapy

Phase 2
Not yet recruiting
Conditions
Locally Advanced Squamous Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-02-28
Last Posted Date
2024-02-28
Lead Sponsor
The First Affiliated Hospital of Xinxiang Medical College
Target Recruit Count
30
Registration Number
NCT06279754

A Clinical Study of Recombinant Human Vascular Endothelial Inhibitor in Combination With PRaG for Advanced Refractory Non-small Cell Lung Cancer

Phase 2
Recruiting
Conditions
Advanced Solid Tumor
Refractory Tumor
Interventions
Radiation: Radiotherapy
Drug: PD-1/PD-L1 inhibitor
Drug: Granulocyte-macrophage colony-stimulating factor subcutaneous injection
Drug: Interleukin 2 subcutaneous injection
First Posted Date
2023-09-21
Last Posted Date
2023-09-21
Lead Sponsor
Second Affiliated Hospital of Soochow University
Target Recruit Count
30
Registration Number
NCT06047860
Locations
🇨🇳

The Second Affiliated Hospital of SchoowUniversity, Suzhou, China

Envafolimab Combined With Endostar and Concurrent Chemoradiotherapy for Locally Advanced Primary Cervical Cancer

Not yet recruiting
Conditions
Cervical Cancer
Interventions
First Posted Date
2023-05-30
Last Posted Date
2023-05-30
Lead Sponsor
Peking University Third Hospital
Target Recruit Count
30
Registration Number
NCT05879796

Radiotherapy Combined With Endostatin and Capecitabine for NPC

Phase 2
Recruiting
Conditions
Nasopharyngeal Carcinoma
Interventions
First Posted Date
2022-08-24
Last Posted Date
2022-08-24
Lead Sponsor
Zhejiang Cancer Hospital
Target Recruit Count
41
Registration Number
NCT05514275
Locations
🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

🇨🇳

People's Hospital of Quzhou, Quzhou, Zhejiang, China

🇨🇳

the First Hospital of Jiaxing, Jiaxing, Zhejiang, China

and more 4 locations

Recombinant Human Angioendostatin /PD-1 Mab Combined With First-line Chemotherapy in the Treatment of Driver Gene Negative Advanced NSCLC

Phase 2
Conditions
Non Small Cell Lung Cancer
Endostatin
Interventions
First Posted Date
2022-07-07
Last Posted Date
2022-07-07
Lead Sponsor
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Target Recruit Count
38
Registration Number
NCT05448781
Locations
🇨🇳

Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China

Modified CV Regimen in Optic Pathway Glioma

Phase 2
Recruiting
Conditions
Optic Glioma
Pediatric Brain Tumor, Optic Nerve Glioma
Interventions
First Posted Date
2022-03-14
Last Posted Date
2024-10-11
Lead Sponsor
Beijing Sanbo Brain Hospital
Target Recruit Count
75
Registration Number
NCT05278715
Locations
🇨🇳

Capital Medical University Sanbo Brain Hospital, Beijing, China

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Phase 4
Conditions
Leptomeningeal Metastasis
Interventions
Drug: intrathcal methotrexate
Drug: Targeted drugs for non-small cell lung cancer
First Posted Date
2020-04-22
Last Posted Date
2020-05-27
Lead Sponsor
Hui Bu
Target Recruit Count
30
Registration Number
NCT04356118

Rh-endostatin Combined With Chemotherapy and Pembrolizumab for Advanced NSCLC

Phase 2
Conditions
Staging IV NSCLC
Interventions
First Posted Date
2019-09-19
Last Posted Date
2020-02-07
Lead Sponsor
Guangzhou Institute of Respiratory Disease
Target Recruit Count
186
Registration Number
NCT04094909
Locations
🇨🇳

Zhou Chengzhi, Guangzhou, Guangdong, China

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