MedPath

Endostatin

Generic Name
Endostatin
Drug Type
Biotech
CAS Number
187888-07-9
Unique Ingredient Identifier
67RHC0R671
Indication

Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.

Second-Line Chemotherapy Combined With Endostatin for Recurrent/Metastatic HN Epithelial Tumors

Phase 2
Conditions
Head and Neck Neoplasms
Interventions
Drug: second-line chemotherapy
First Posted Date
2019-06-18
Last Posted Date
2020-10-23
Lead Sponsor
Sun Yan
Target Recruit Count
53
Registration Number
NCT03989830
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

Recombinant Human Endostatin in Combination With XELOX Therapy in Patient With Advanced Colorectal Cancer.

First Posted Date
2018-07-05
Last Posted Date
2019-04-04
Lead Sponsor
Sichuan Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT03577392
Locations
🇨🇳

Sichuan Provincial People Hospital, Chengdu, Sichuan, China

Recombinant Human Endostatin(Rh-endostatin) Combine With Radiotherapy in the Treatment of Hepatocellular Carcinoma(HCC)

Phase 2
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2017-07-05
Last Posted Date
2017-07-05
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
61
Registration Number
NCT03208335
Locations
🇨🇳

Chinese PLA Gereral Hospital, Beijing, Beijing, China

Recombinant Endostatin Combined With Vinorelbine and Cisplatin in Patients With Advanced Non-small Cell Lung Cancer

Phase 3
Completed
Conditions
Advanced Non-small Cell Lung Cancer
Interventions
Drug: Placebos
First Posted Date
2017-04-17
Last Posted Date
2017-04-17
Lead Sponsor
Jiangsu Wuzhong Pharmaceutical Group Co., Ltd.
Target Recruit Count
560
Registration Number
NCT03117335
Locations
🇨🇳

Bengbu medical college affiliated hospital, Bengbu, Anhui, China

🇨🇳

Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing, China

🇨🇳

The first affiliated hospital, anhui medical university, Hefei, Anhui, China

and more 34 locations

Rh-endostatin in Combination With Dacarbazine and Cisplatin as the First Line Therapy for Metastatic Melanoma

Phase 2
Conditions
Melanoma
Interventions
First Posted Date
2017-03-29
Last Posted Date
2017-03-29
Lead Sponsor
Peking University Cancer Hospital & Institute
Target Recruit Count
70
Registration Number
NCT03095079
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

Endostar Durative Transfusion Combined With Chemotherapy in the Treatment of Advanced Lung Adenocarcinoma

First Posted Date
2016-06-17
Last Posted Date
2016-06-21
Lead Sponsor
Anhui Provincial Hospital
Target Recruit Count
100
Registration Number
NCT02804646
Locations
🇨🇳

Anhui provincial hospital, Hefei, Anhui, China

Endostatin in Combination With Oxaliplatin and Radiotherapy in Esophageal Cancer Patients.

Phase 2
Conditions
Esophageal Cancer
Endostatin
Interventions
Radiation: Radiotherapy
First Posted Date
2016-04-20
Last Posted Date
2016-04-20
Lead Sponsor
Hangzhou Cancer Hospital
Target Recruit Count
22
Registration Number
NCT02745561
Locations
🇨🇳

Hangzhou Cancer Hospital, Hangzhou, Zhejiang, China

Endostar for Locally Recurrent Nasopharyngeal Carcinoma

Phase 2
Conditions
Nasopharyngeal Carcinoma
Interventions
Radiation: IMRT
First Posted Date
2015-12-21
Last Posted Date
2021-02-03
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
96
Registration Number
NCT02636231
Locations
🇨🇳

Cancer Center of Guangzhou Medical University, Guangzhou, Guangdong, China

🇨🇳

The First Hospital of Gannan Medical University, GanZhou, Jiangxi, China

🇨🇳

The First Affiliated Hospital of Clinical Medicine of G.D.P.U., Guangzhou, Guangdong, China

and more 5 locations

E10A for the Treatment of Squamous Cell Carcinoma of the Head and Neck

Phase 3
Conditions
Head and Neck Neoplasms
Interventions
First Posted Date
2015-12-15
Last Posted Date
2015-12-15
Lead Sponsor
Guangzhou Double Bioproducts Co., Ltd
Target Recruit Count
540
Registration Number
NCT02630264
Locations
🇨🇳

Guangzhou DB, Gaungzhou, Guangdong, China

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