MedPath

Endostatin

Generic Name
Endostatin
Drug Type
Biotech
CAS Number
187888-07-9
Unique Ingredient Identifier
67RHC0R671
Indication

Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.

A Phase II Clinical Trial of Chemotherapy With or Without Endostar® Continuous Intravenous Infusion in Refractory NPC

First Posted Date
2015-10-28
Last Posted Date
2017-12-22
Lead Sponsor
Yun-fei Xia
Target Recruit Count
328
Registration Number
NCT02590133
Locations
🇨🇳

Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China

Recombinant Human Endostatin Combined With NP in Neoadjuvant Chemotherapy of Stage ⅢA NSCLC

Phase 4
Completed
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2015-07-14
Last Posted Date
2015-07-14
Lead Sponsor
Tianjin Medical University Cancer Institute and Hospital
Target Recruit Count
30
Registration Number
NCT02497118
Locations
🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

Endostar Combination With Chemotherapy and EGFR-TKI in Lung Cancer Rechallenging Treatment After Acquired Resistance.

Phase 2
Conditions
Lung Cancer
Interventions
First Posted Date
2015-01-29
Last Posted Date
2015-01-29
Lead Sponsor
Peking University Third Hospital
Target Recruit Count
60
Registration Number
NCT02350361
Locations
🇨🇳

Peking University Third Hospital, Beijing, China

Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Phase 2
Completed
Conditions
Vestibular Schwannoma
Neurofibromatosis Type 2
Interventions
First Posted Date
2014-04-04
Last Posted Date
2017-02-09
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
20
Registration Number
NCT02104323
Locations
🇨🇳

Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, Beijing, China

Intrapleural Administration of Bevacizumab Versus Endostar for Pleural Effusions in NSCLC

Phase 2
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2013-12-09
Last Posted Date
2013-12-20
Lead Sponsor
Zhejiang University
Target Recruit Count
20
Registration Number
NCT02005120
Locations
🇨🇳

Qiong Zhao, Hangzhou, Zhejiang, China

🇨🇳

The first affiliated hospital, Zhejiang University, Hangzhou, Zhejiang, China

Comparison of Postoperative Adjuvant Chemotherapy With/Without Rh-endostatin on Non-small Cell Lung Cancer in PhaseⅠB

Phase 3
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2013-12-04
Last Posted Date
2013-12-04
Lead Sponsor
Xinjiang Medical University
Target Recruit Count
392
Registration Number
NCT02001168
Locations
🇨🇳

Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC

Phase 1
Completed
Conditions
Stage III Non-small-Cell Lung Cancer
Interventions
Drug: cisplatinum (50mg/m2) IV (in the vein) on day 1 and day 8 of a 28-day cycle for 2 cycles
Other: laboratory biomarker analysis
Other: CT perfusion imaging
First Posted Date
2012-11-27
Last Posted Date
2017-07-14
Lead Sponsor
Zhejiang Cancer Hospital
Target Recruit Count
73
Registration Number
NCT01733589
Locations
🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer

Phase 2
Conditions
1、Enough Cases
2、Elekta Precise 1343 Digital Control Electron Linear Accelerator
Can Undertake Nasopharyngeal Carcinoma Specimens in the Materia,
Image Department of Nose Pharynx Ministry MRI Dynamic Testing,
Interventions
First Posted Date
2012-09-21
Last Posted Date
2013-03-12
Lead Sponsor
Jin Feng
Target Recruit Count
60
Registration Number
NCT01689558
Locations
🇨🇳

Cancer Hospital of Guizhou province, Guiyang, Guizhou, China

Endostar Combination With Chemotherapy for the Metastatic Nasopharyngeal Carcinoma

Phase 2
Conditions
Nasopharyngeal Carcinoma
Interventions
First Posted Date
2012-06-05
Last Posted Date
2014-02-19
Lead Sponsor
Zhejiang Cancer Hospital
Target Recruit Count
30
Registration Number
NCT01612286
Locations
🇨🇳

Zhejiang cancer hospital, Hangzhou, Zhejiang, China

Efficacy and Safety Study of Recombinant Endostatin Combined With Chemotherapy to Treat Advanced Colorectal Cancer

First Posted Date
2012-02-08
Last Posted Date
2013-11-27
Lead Sponsor
Chinese Academy of Medical Sciences
Target Recruit Count
51
Registration Number
NCT01529164
Locations
🇨🇳

Cancer hospital & Institute,Chinese Academy of Medical Sciences, Beijing, Beijing, China

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