Desflurane

Generic Name: Desflurane

Brand Names: Suprane

Drug Type: Small Molecule

Chemical Formula: C_₃H_₂F_₆O

CAS Number: 57041-67-5

Unique Ingredient Identifier: CRS35BZ94Q

Background: Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.
...

Indication: Desflurane is indicated for the induction and maintenance of anesthesia in adults, as well as the maintenance of anesthesia in pediatric patients.

Associated Conditions: -

Associated Therapies: Induction and Maintenance of General Anesthesia, Maintenance of anesthesia therapy

Clinical Trials

Automated Closed Loop Propofol Anaesthesia Versus Desflurane Inhalation Anaesthesia In Bariatric Surgery

Phase 4

Completed

Conditions: Anesthesia; Bariatric Surgery

Interventions: Drug: Propofol
Drug: Desflurane

First Posted Date: 2017-04-04

Last Posted Date: 2019-12-23

Lead Sponsor: Dr Nitin Sethi

Target Recruit Count: 40

Registration Number: NCT03099616

Locations: 🇮🇳
Sir Ganga Ram Hospital, New Delhi, Delhi, India

The Change of Tissue Oxygen Saturation Following Volatile Anesthesia

Completed

Conditions: Healthy
Aging

First Posted Date: 2017-02-23

Last Posted Date: 2020-04-14

Lead Sponsor: Pusan National University Hospital

Target Recruit Count: 60

Registration Number: NCT03060798

Locations: 🇰🇷
Hyeon Jeong Lee, Busan, Korea, Republic of

Anaesthesia for Laparoscopic Sleeve Gastrectomy

Not Applicable

Completed

Conditions: Obese

Interventions: Drug: Propofol
Drug: Desflurane
Drug: Remifentanil
Drug: Dexmedetomidine

First Posted Date: 2017-01-24

Last Posted Date: 2020-09-16

Lead Sponsor: Menoufia University

Target Recruit Count: 100

Registration Number: NCT03029715

IOP Changes With Different Anesthetic Agents During Laparoscopic Colorectal Surgery

Not Applicable

Completed

Conditions: Intraocular Pressure

Interventions: Drug: Desflurane
Drug: Propofol

First Posted Date: 2017-01-10

Last Posted Date: 2017-04-26

Lead Sponsor: Saint Vincent's Hospital, Korea

Target Recruit Count: 50

Registration Number: NCT03016234

Locations: 🇰🇷
Saint Vincent's Hospital, Korea, Suwon, Gyonggido, Korea, Republic of

Blood Levels of Sevoflurane and Desflurane

Completed

Conditions: Anesthetics, Inhalation

Interventions: Drug: Sevoflurane
Drug: Desflurane

First Posted Date: 2017-01-10

Last Posted Date: 2018-03-05

Lead Sponsor: Cukurova University

Target Recruit Count: 16

Registration Number: NCT03015350

Locations: 🇹🇷
Ebru Biricik, Adana, In The USA Or Canada, Please Select..., Turkey

The Effect of Desflurane vs Sevoflurane on Perioperative Respiratory Complications in Laryngeal Mask Airway Anesthesia

Phase 4

Conditions: Anesthesia; Adverse Effect
Laryngeal Masks
Respiratory System Abnormalities

Interventions: Drug: Desflurane
Drug: Sevoflurane

First Posted Date: 2016-12-30

Last Posted Date: 2018-12-28

Lead Sponsor: Chiang Mai University

Target Recruit Count: 220

Registration Number: NCT03006250

Locations: 🇹🇭
Chiang Mai University, Chiang Mai, Thailand

Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery

Phase 4

Completed

Conditions: Postoperative Cognitive Function

Interventions: Drug: Desflurane
Drug: Propofol

First Posted Date: 2016-12-08

Last Posted Date: 2016-12-08

Lead Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

Target Recruit Count: 100

Registration Number: NCT02987218

Locations: 🇮🇳
Postgraduate institute of medical education and research, Chandigarh, India

The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients

Phase 2

Completed

Conditions: Down Syndrome

Interventions: Drug: Sevoflurane
Drug: Desflurane

First Posted Date: 2016-11-22

Last Posted Date: 2020-06-09

Lead Sponsor: Asklepieion Voulas General Hospital

Target Recruit Count: 39

Registration Number: NCT02971254

Locations: 🇬🇷
Gkliatis Emmanouil, Athens, Greece

Comparison of Postoperative Delirium in Patients Anaesthetised With Isoflurane and Desflurane During Spinal Surgery

Phase 4

Completed

Conditions: Postoperative Delirium

Interventions: Drug: Isoflurane
Drug: Desflurane

First Posted Date: 2016-10-06

Last Posted Date: 2019-06-19

Lead Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

Target Recruit Count: 60

Registration Number: NCT02925611

Locations: 🇮🇳
Postgraduate Institute of Medical Education and Research, Chandigarh, India

Comparison of Desflurane Anesthesia Versus TIVA-TCI in Patients Undergoing Ophthalmic Ambulatory Surgery

Not Applicable

Completed

Conditions: Anesthesia
Ophthalmic
Surgery

Interventions: Procedure: total intravenous anesthesia
Drug: desflurane
Drug: Propofol
Procedure: inhalation anesthesia
Drug: Remifentanil

First Posted Date: 2016-10-04

Last Posted Date: 2018-01-23

Lead Sponsor: Xiaoliang Gan

Target Recruit Count: 209

Registration Number: NCT02922660

Locations: 🇨🇳
Zhongshan ophthalmic center, Sun Yat-sen University, Guangzhou, Guangdong, China

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