MedPath

Incomplete Freund's adjuvant

Generic Name
Incomplete Freund's adjuvant
Drug Type
Biotech
Unique Ingredient Identifier
Y9DQK7DB5U

Vaccine Therapy With or Without Sargramostim in Treating Patients Who Have Undergone Surgery for Melanoma

Phase 2
Completed
Conditions
Iris Melanoma
Stage IIC Melanoma
Stage IV Melanoma
Extraocular Extension Melanoma
Stage IIIC Melanoma
Ciliary Body and Choroid Melanoma, Medium/Large Size
Stage IIB Melanoma
Stage IIIA Melanoma
Stage IIIB Melanoma
Interventions
Biological: tyrosinase peptide
Biological: gp100 antigen
Biological: MART-1 antigen
Biological: incomplete Freund's adjuvant
Biological: sargramostim
Other: laboratory biomarker analysis
First Posted Date
2004-08-05
Last Posted Date
2015-04-15
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00089063
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

Vaccine Therapy in Treating Patients With Stage IIC-IV Melanoma

Phase 2
Completed
Conditions
Recurrent Intraocular Melanoma
Recurrent Melanoma
Stage IIIC Melanoma
Ciliary Body and Choroid Melanoma, Small Size
Stage IIIA Melanoma
Stage IIIB Intraocular Melanoma
Extraocular Extension Melanoma
Iris Melanoma
Ciliary Body and Choroid Melanoma, Medium/Large Size
Stage IIIB Melanoma
Interventions
Biological: gp100 antigen
Biological: tyrosinase peptide
Biological: recombinant MAGE-3.1 antigen
Biological: multi-epitope melanoma peptide vaccine
Biological: incomplete Freund's adjuvant
Other: laboratory biomarker analysis
First Posted Date
2004-06-11
Last Posted Date
2014-05-22
Lead Sponsor
University of Southern California
Target Recruit Count
42
Registration Number
NCT00085189
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

Vaccine Treatment in Combination With IL-2 and Treated Lymphocytes for Advanced Melanoma

Phase 2
Completed
Conditions
Melanoma
First Posted Date
2004-03-29
Last Posted Date
2012-06-14
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
58
Registration Number
NCT00080353
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

Peptide Vaccination for Patients at High Risk for Recurrent Melanoma

Phase 2
Completed
Conditions
Melanoma
Interventions
First Posted Date
2003-04-28
Last Posted Date
2012-10-23
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
138
Registration Number
NCT00059475
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

Aldesleukin With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Melanoma

Phase 3
Completed
Conditions
Recurrent Melanoma
Stage IIIA Skin Melanoma
Stage IIIB Skin Melanoma
Stage IIIC Skin Melanoma
Stage IV Skin Melanoma
Interventions
Biological: Aldesleukin
Other: Quality-of-Life Assessment
Biological: gp100 Antigen
Other: Questionnaire Administration
Other: Laboratory Biomarker Analysis
First Posted Date
2003-01-27
Last Posted Date
2017-11-20
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
185
Registration Number
NCT00019682
Locations
🇺🇸

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States

🇺🇸

The Christ Hospital, Cincinnati, Ohio, United States

🇺🇸

University of Colorado Cancer Center - Anschutz Cancer Pavilion, Aurora, Colorado, United States

and more 16 locations

Vaccine Therapy Plus Immune Adjuvant in Treating Patients With Chronic Myeloid Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Phase 1
Completed
Conditions
Accelerated Phase Chronic Myelogenous Leukemia
Adult Acute Myeloid Leukemia in Remission
Chronic Phase Chronic Myelogenous Leukemia
Previously Treated Myelodysplastic Syndromes
Refractory Anemia With Excess Blasts
Refractory Anemia With Excess Blasts in Transformation
Relapsing Chronic Myelogenous Leukemia
Interventions
Biological: PR1 leukemia peptide vaccine
Biological: sargramostim
Other: laboratory biomarker analysis
First Posted Date
2003-01-27
Last Posted Date
2013-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
69
Registration Number
NCT00004918
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Vaccination With Tetanus and KLH to Assess Immune Responses.

Terminated
Conditions
Cancer
Interventions
Biological: Biosyn KLH
Biological: Intracel KLH Vaccine
Biological: Tetanus toxoid
First Posted Date
1999-11-04
Last Posted Date
2017-11-29
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
112
Registration Number
NCT00000105
Locations
🇺🇸

Division of Hematology, Oncology, and Transplantation 420 Delaware St., SE, Box 806 Mayo, Minneapolis, Minnesota, United States

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