MedPath

Incomplete Freund's adjuvant

Generic Name
Incomplete Freund's adjuvant
Drug Type
Biotech
Unique Ingredient Identifier
Y9DQK7DB5U

KLH Challenge to Explore the Human Immune Response

Not Applicable
Recruiting
Conditions
Immune Response
Interventions
Biological: Keyhole-Limpet Hemocyanin
Drug: Saline
First Posted Date
2023-05-25
Last Posted Date
2023-05-25
Lead Sponsor
University of Oxford
Target Recruit Count
39
Registration Number
NCT05876195
Locations
🇬🇧

NIHR Oxford Experimental Medicine Clinical Research Facility, Oxford, United Kingdom

Multi Peptide Vaccination with XS15 in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed Glioblastoma

Phase 1
Completed
Conditions
Glioblastoma Multiforme of Brain
Interventions
First Posted Date
2021-04-13
Last Posted Date
2025-01-10
Lead Sponsor
University Hospital Tuebingen
Target Recruit Count
15
Registration Number
NCT04842513
Locations
🇩🇪

University Hospital Tübingen, Tübingen, BW, Germany

Study of Pembrolizumab Plus SurVaxM for Glioblastoma at First Recurrence

Phase 2
Completed
Conditions
Recurrent Glioblastoma
Interventions
First Posted Date
2019-07-10
Last Posted Date
2024-08-28
Lead Sponsor
David Peereboom
Target Recruit Count
41
Registration Number
NCT04013672
Locations
🇺🇸

Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

Phase 1
Recruiting
Conditions
Lung Atypical Carcinoid Tumor
Metastatic Pancreatic Neuroendocrine Tumor
Lung Typical Carcinoid Tumor
Interventions
First Posted Date
2019-03-19
Last Posted Date
2024-12-18
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
14
Registration Number
NCT03879694
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2
Active, not recruiting
Conditions
Glioblastoma
Gliosarcoma
Interventions
First Posted Date
2015-05-28
Last Posted Date
2025-03-03
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
66
Registration Number
NCT02455557
Locations
🇺🇸

Dana-Farber Harvard Cancer Center, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

and more 2 locations

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Phase 1
Active, not recruiting
Conditions
Partial Response of Multiple Myeloma or Plasma Cell Leukemia
Plasma Cell Myeloma
Interventions
First Posted Date
2015-01-08
Last Posted Date
2025-05-11
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
18
Registration Number
NCT02334865
Locations
🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission

Phase 1
Completed
Conditions
Adult Acute Myeloid Leukemia in Remission
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Adult Acute Myeloid Leukemia With Del(5q)
Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)
Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)
Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)
Interventions
Biological: WT1 126-134 peptide vaccine
Biological: basiliximab
Other: laboratory biomarker analysis
First Posted Date
2013-04-29
Last Posted Date
2018-03-09
Lead Sponsor
University of Chicago
Target Recruit Count
7
Registration Number
NCT01842139
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery

Early Phase 1
Completed
Conditions
Recurrent Melanoma
Stage IIA Melanoma
Stage IIB Melanoma
Stage IIC Melanoma
Stage IIIA Melanoma
Stage IIIB Melanoma
Stage IIIC Melanoma
Stage IV Melanoma
Interventions
Biological: MART-1 antigen
Other: laboratory biomarker analysis
First Posted Date
2012-12-12
Last Posted Date
2018-10-09
Lead Sponsor
Mayo Clinic
Target Recruit Count
30
Registration Number
NCT01748747
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558

Phase 1
Completed
Conditions
Melanoma (Skin)
Interventions
Biological: MART-1
Biological: NY-ESO-1
Biological: BMS-936558
First Posted Date
2010-08-06
Last Posted Date
2023-01-18
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Target Recruit Count
127
Registration Number
NCT01176461
Locations
🇺🇸

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Skin Cancer
Melanoma
Interventions
First Posted Date
2009-06-18
Last Posted Date
2015-10-28
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
4
Registration Number
NCT00923195
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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