MedPath

mRNA-1273.529

Generic Name
mRNA-1273.529

COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)

Phase 2
Completed
Conditions
COVID-19
Interventions
Biological: BNT162b2 (B.1.1.529)
Biological: BNT162b2 bivalent (wildtype and Omicron BA.1)
Biological: BNT162b2 bivalent (wildtype and Omicron BA.4/BA.5)
Other: Sodium Chloride, 0.9%
Biological: BNT162b2 (B.1.351)
Biological: CoV2 preS dTM/D614
Biological: CoV2 preS dTM [B.1.351]
Biological: CoV2 preS dTM/D614+B.1.351
First Posted Date
2022-03-21
Last Posted Date
2025-03-14
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1270
Registration Number
NCT05289037
Locations
🇺🇸

University of California, San Diego (UCSD) - Antiviral Research Center (AVRC), San Diego, California, United States

🇺🇸

Baylor College of Medicine, Houston, Texas, United States

🇺🇸

University of Alabama at Birmingham School of Medicine - Alabama Vaccine Research Clinic, Birmingham, Alabama, United States

and more 19 locations

A Study to Evaluate the Immunogenicity and Safety of mRNA Vaccine Boosters for SARS-CoV-2 (COVID-19) Variants

First Posted Date
2021-06-15
Last Posted Date
2025-02-28
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
5161
Registration Number
NCT04927065
Locations
🇺🇸

Research Centers of America, Hollywood, Florida, United States

🇺🇸

Jacksonville Center For Clinical Research, Jacksonville, Florida, United States

🇺🇸

Meridian Clinical Research (Iowa), Sioux City, Iowa, United States

and more 20 locations
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