Glimepiride

Generic Name
Glimepiride
Brand Names
Duetact, Tandemact
Drug Type
Small Molecule
Chemical Formula
C24H34N4O5S
CAS Number
93479-97-1
Unique Ingredient Identifier
6KY687524K
Background

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure a...

Indication

Glimepiride is indicated for the management of type 2 diabetes in adults as an adjunct to diet and exercise to improve glycemic control as monotherapy.
...

Associated Conditions
Type 2 Diabetes Mellitus
Associated Therapies
-

A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes

First Posted Date
2007-03-20
Last Posted Date
2016-05-16
Lead Sponsor
Sanofi
Target Recruit Count
508
Registration Number
NCT00449605
Locations
🇨🇱

Sanofi-aventis adminsitrative office, Santiago, Chile

🇸🇪

Sanofi-Aventis Administrative Office, Bromma, Sweden

Phase III Study for Glimepiride + Metformin Hydrochloride (Amaryl M) Slow Release (SR)

Phase 3
Completed
Conditions
First Posted Date
2007-02-21
Last Posted Date
2007-11-29
Lead Sponsor
Handok Inc.
Target Recruit Count
188
Registration Number
NCT00437554
Locations
🇰🇷

Handok, Seoul, Korea, Republic of

Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes

First Posted Date
2007-01-26
Last Posted Date
2018-09-05
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
227
Registration Number
NCT00427154
Locations
🇺🇸

Novo Nordisk Investigational Site, Tacoma, Washington, United States

Insulin Glulisine in Type 2 Diabetic Patients

First Posted Date
2006-08-07
Last Posted Date
2011-08-08
Lead Sponsor
Sanofi
Target Recruit Count
106
Registration Number
NCT00360698
Locations
🇷🇺

Sanofi-Aventis, Moscow, Russian Federation

🇬🇧

Sanofi-aventis, Guildford, United Kingdom

Exenatide Versus Glimepiride in Patients With Type 2 Diabetes

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-08-02
Last Posted Date
2015-09-15
Lead Sponsor
AstraZeneca
Target Recruit Count
1029
Registration Number
NCT00359762
Locations
🇬🇧

Research Site, Wiltshire, United Kingdom

Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus

Phase 3
Completed
Conditions
First Posted Date
2006-07-19
Last Posted Date
2011-01-11
Lead Sponsor
Sanofi
Target Recruit Count
100
Registration Number
NCT00353691
Locations
🇺🇸

Sanofi-Aventis, Bridgewater, New Jersey, United States

Safety and Efficacy of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

First Posted Date
2006-06-23
Last Posted Date
2017-03-01
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
363
Registration Number
NCT00343980
Locations
🇹🇷

Novo Nordisk Investigational Site, Istanbul, Turkey

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Phase 3
Completed
Conditions
First Posted Date
2006-05-31
Last Posted Date
2017-01-26
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
584
Registration Number
NCT00331851
Locations
🇬🇧

Novo Nordisk Investigational Site, Watford, United Kingdom

To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together

First Posted Date
2006-04-26
Last Posted Date
2017-03-07
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
1091
Registration Number
NCT00318461
Locations
🇬🇧

Novo Nordisk Investigational Site, Sunbury on Thames, United Kingdom

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Phase 3
Completed
Conditions
First Posted Date
2006-04-26
Last Posted Date
2017-01-25
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
1041
Registration Number
NCT00318422
Locations
🇹🇷

Novo Nordisk Investigational Site, Izmir, Turkey

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