MedPath

Glucose

Generic Name
Glucose
Brand Names
Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One
Drug Type
Small Molecule
Unique Ingredient Identifier
IY9XDZ35W2
Background

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication

Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions
Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis
Associated Therapies
Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSF

Phase 3
Completed
Conditions
Neutropenia in Prematures
Interventions
Drug: dextrose 5%
First Posted Date
2005-09-21
Last Posted Date
2007-11-29
Lead Sponsor
University Hospital, Strasbourg, France
Target Recruit Count
200
Registration Number
NCT00213759
Locations
🇫🇷

André Labbe, Clermont-Ferrand, France

🇫🇷

Alain Menget, Besancon, France

🇫🇷

Marie Thieuleux, Calais, France

and more 6 locations

Improving Memory in Patients With Multiple Sclerosis

Phase 3
Withdrawn
Conditions
Multiple Sclerosis
First Posted Date
2003-06-19
Last Posted Date
2017-04-25
Lead Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Registration Number
NCT00062972
Locations
🇺🇸

University Hospital and Medical Center, Stony Brook, New York, United States

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Terminated
Conditions
Cystic Fibrosis
First Posted Date
2001-04-11
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
36
Registration Number
NCT00014768
Locations
🇺🇸

University of Utah School of Medicine, Salt Lake City, Utah, United States

Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion

Not Applicable
Conditions
Infant, Low Birth Weight
Hyperglycemia
First Posted Date
2000-06-05
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
96
Registration Number
NCT00005889
Locations
🇺🇸

Baylor College of Medicine, Houston, Texas, United States

Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

Not Applicable
Completed
Conditions
Parkinson Disease
First Posted Date
1999-10-19
Last Posted Date
2005-12-01
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
120
Registration Number
NCT00004451
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

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