MedPath

Pseudoephedrine

Generic Name
Pseudoephedrine
Brand Names
Advil Cold and Sinus, Alavert D, Aleve-D, Allegra-D, Aller-tec D, Allerclear, Bromfed DM, Cheratussin Dac, Clarinex-D, Claritin-D, Codar D, Covan, Entex T, Lodrane D, Mar-cof BP, Mucinex D, Nexafed, Pseudodine C, Rescon Tablets, Semprex-D, Stahist Ad Liquid, Sudafed, Sudafed Sinus & Pain, Sudogest, Triacin-C, Tusnel C, Wal Zyr D, Wal-act, Wal-itin D, Wal-phed, Zephrex-D, Zyrtec-D
Drug Type
Small Molecule
Chemical Formula
C10H15NO
CAS Number
90-82-4
Unique Ingredient Identifier
7CUC9DDI9F

Overview

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described in dogs in 1927.

Background

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described in dogs in 1927.

Indication

Pseudoephedrine is a sympathomimetic amine used for its decongestant activity.

Associated Conditions

  • Allergic Reaction
  • Allergic Rhinitis (AR)
  • Common Cold
  • Common Cold Associated With Cough
  • Cough
  • Cough caused by Common Cold
  • Eye allergy
  • Fever
  • Flu caused by Influenza
  • Headache
  • Irritative cough
  • Nasal Allergies
  • Nasal Congestion
  • Nasal Congestion caused by Common Cold
  • Pain
  • Perennial Allergy
  • Priapism
  • Respiratory Allergy
  • Rhinorrhoea
  • Seasonal Allergic Rhinitis
  • Seasonal Allergies
  • Sinus Congestion
  • Sinusitis
  • Sneezing
  • Sore Throat
  • Symptoms of Acute Bronchitis Accompanied by Coughing
  • Throat irritation
  • Upper Respiratory Tract Infection
  • Upper respiratory tract congestion
  • Upper respiratory tract signs and symptoms
  • Cold or flu syndrome
  • Dry cough
  • Minor aches and pains
  • Sinus pain
  • Watery itchy eyes

FDA Approved Products

Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide
Manufacturer:Chartwell RX, LLC
Route:ORAL
Strength:30 mg in 5 mL
Approved: 2023/01/24
NDC:62135-302
Atuss DS Tannate Suspension
Manufacturer:Atley Pharmaceuticals, Inc.
Route:ORAL
Strength:30 mg in 5 mL
Approved: 2010/02/22
NDC:59702-800
Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:30 mg in 5 mL
Approved: 2021/11/22
NDC:50090-5625
Brompheniramine maleate, pseudoephedrine hydrochloride,
Manufacturer:Eywa Pharma Inc
Route:ORAL
Strength:30 mg in 5 mL
Approved: 2020/06/26
NDC:71930-026
Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide
Manufacturer:Padagis US LLC
Route:ORAL
Strength:30 mg in 5 mL
Approved: 2021/11/22
NDC:0574-1104

Singapore Approved Products

POLARINE TABLET
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED, SUNWARD PHARMACEUTICAL SDN BHD
Form:TABLET
Strength:60 mg
Online:Yes
Approved: 1994/01/18
Approval:SIN07612P
CLARITYN-D 12HOUR REPETABS
Manufacturer:SAG Manufacturing SLU
Form:TABLET, SUGAR COATED
Strength:120 mg
Online:Yes
Approved: 1992/11/06
Approval:SIN07282P
FEBRICOL TABLET
Manufacturer:XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 2001/04/11
Approval:SIN11488P
DECONDINE SYRUP
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED, SUNWARD PHARMACEUTICAL SDN BHD
Form:SYRUP
Strength:30 mg/5 ml
Online:Yes
Approved: 1989/06/12
Approval:SIN03181P
ZYRTEC-D
Manufacturer:UCB FARCHIM SA, AESICA PHARMACEUTICALS S.R.L
Form:TABLET, FILM COATED
Strength:120 MG
Online:Yes
Approved: 2005/07/04
Approval:SIN13139P

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