Ivermectin
- Generic Name
- Ivermectin
- Brand Names
- Sklice, Soolantra, Stromectol
- Drug Type
- Small Molecule
- Chemical Formula
- C95H146O28
- CAS Number
- 70288-86-7
- Unique Ingredient Identifier
- 8883YP2R6D
- Background
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A (22,23-dihydroavermectin B) and 10%...
- Indication
Administered topically, ivermectin cream is indicated for the treatment of inflammatory lesions associated with rosacea. An over-the-counter ivermection lotion is commercially available and indicated for the topical treatment of head lice infestations in patients ≥6 months of age.
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- Associated Conditions
- Ascariasis, Demodex Infestation, Enterobiasis, Filariasis caused by Loa Loa, Gnathostomiasis, Head Lice Infestation, Malaria, Myiasis, Onchocerciasis caused by Infection with Onchocerca volvulus, Rosacea, Scabies, Strongyloidiasis caused by Strongyloides Stercoralis Infection, Trichuriasis
- Associated Therapies
- -
Adjunctive Ivermectin Mass Drug Administration for Malaria Control
- First Posted Date
- 2021-04-14
- Last Posted Date
- 2022-02-24
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 24000
- Registration Number
- NCT04844905
- Locations
- 🇬🇼
Bijagos Archipelago (islands), Bissau, Guinea-Bissau
Clinical Trial to "Study the Efficacy and Therapeutic Safety of Ivermectin: (SAINTBO)
- First Posted Date
- 2021-04-08
- Last Posted Date
- 2021-04-08
- Lead Sponsor
- Universidad Mayor de San Simón
- Target Recruit Count
- 90
- Registration Number
- NCT04836299
- Locations
- 🇧🇴
Universidad Mayor de San Simón, Cochabamba, Bolivia
Ivermectin Reproposing for Mild Stage COVID-19 Outpatients
- Conditions
- Interventions
- First Posted Date
- 2021-03-05
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Ministry of Public Health, Argentina
- Target Recruit Count
- 254
- Registration Number
- NCT04784481
- Locations
- 🇦🇷
SI.PRO.SA, Ministerio de Salud Pública, Tucumán, Argentina
Comparative Therapeutic Efficacy and Safety of Different Antiviral and Anti Inflammatory Drugs in COVID-19 Patients.
- Conditions
- Interventions
- First Posted Date
- 2021-03-03
- Last Posted Date
- 2021-03-17
- Lead Sponsor
- October 6 University
- Target Recruit Count
- 150
- Registration Number
- NCT04779047
- Locations
- 🇪🇬
Beni-suef University, Banī Suwayf, Egypt
Adverse Effects of Ivermectin Used in Egypt During COVID-19
- First Posted Date
- 2021-02-10
- Last Posted Date
- 2021-02-10
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 200
- Registration Number
- NCT04747678
- Locations
- 🇪🇬
Ahmed Mansour, Shibīn Al Kawm, Menoufia, Egypt
Ivermectin Role in Covid-19 Clinical Trial
- First Posted Date
- 2021-02-09
- Last Posted Date
- 2021-02-09
- Lead Sponsor
- Elaraby Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT04746365
- Locations
- 🇪🇬
Shebin-Elkom teaching hospital, Shibīn Al Kawm, Menoufia, Egypt
Effectiveness of Ivermectin in SARS-CoV-2/COVID-19 Patients
- First Posted Date
- 2021-02-04
- Last Posted Date
- 2021-02-04
- Lead Sponsor
- FMH College of Medicine and Dentistry
- Target Recruit Count
- 50
- Registration Number
- NCT04739410
- Locations
- 🇵🇰
Aijaz Zeeshan Khan Chachar, Lahore, Punjab, Pakistan
Montelukast - a Treatment Choice for COVID-19
- Conditions
- Interventions
- First Posted Date
- 2021-01-19
- Last Posted Date
- 2021-01-19
- Lead Sponsor
- University of Sargodha
- Target Recruit Count
- 150
- Registration Number
- NCT04714515
- Locations
- 🇨🇳
Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China, Shanghai, China
🇵🇰Shaukat Khanum Memorial Cancer Hospital & Research Centre, Johar Town, Lahore, Pakistan, Lahore, Punjab, Pakistan
Prevention and Treatment for COVID -19 (Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2) Associated Severe Pneumonia in the Gambia
- First Posted Date
- 2021-01-11
- Last Posted Date
- 2021-06-04
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 1200
- Registration Number
- NCT04703608
- Locations
- 🇬🇲
Mrcg@Lshtm, Fajara, Gambia
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
- Conditions
- Interventions
- First Posted Date
- 2020-12-16
- Last Posted Date
- 2020-12-16
- Lead Sponsor
- Benha University
- Target Recruit Count
- 600
- Registration Number
- NCT04668469
- Locations
- 🇪🇬
Benha Faculty of Medicine, Benha University, Banhā, Qaluopia, Egypt
Drug Development Updates
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