Ivermectin

Generic Name
Ivermectin
Brand Names
Sklice, Soolantra, Stromectol
Drug Type
Small Molecule
Chemical Formula
C95H146O28
CAS Number
70288-86-7
Unique Ingredient Identifier
8883YP2R6D
Background

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A (22,23-dihydroavermectin B) and 10%...

Indication

Administered topically, ivermectin cream is indicated for the treatment of inflammatory lesions associated with rosacea. An over-the-counter ivermection lotion is commercially available and indicated for the topical treatment of head lice infestations in patients ≥6 months of age.
...

Associated Conditions
Ascariasis, Demodex Infestation, Enterobiasis, Filariasis caused by Loa Loa, Gnathostomiasis, Head Lice Infestation, Malaria, Myiasis, Onchocerciasis caused by Infection with Onchocerca volvulus, Rosacea, Scabies, Strongyloidiasis caused by Strongyloides Stercoralis Infection, Trichuriasis
Associated Therapies
-
Clinical Trials
Related News

Comparative Study of Hydroxychloroquine and Ivermectin in COVID-19 Prophylaxis

First Posted Date
2020-05-12
Last Posted Date
2020-10-06
Lead Sponsor
Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Target Recruit Count
400
Registration Number
NCT04384458
Locations
🇧🇷

Drug Research and Development Center (NPDM), Federal University of Ceará (UFC), Fortaleza, Ceará, Brazil

Novel Agents for Treatment of High-risk COVID-19 Positive Patients

First Posted Date
2020-05-05
Last Posted Date
2022-01-20
Lead Sponsor
Susanne Arnold
Target Recruit Count
13
Registration Number
NCT04374019
Locations
🇺🇸

University of Kentucky Markey Cancer Center, Lexington, Kentucky, United States

Max Ivermectin- COVID 19 Study Versus Standard of Care Treatment for COVID 19 Cases. A Pilot Study

Not Applicable
Conditions
COVID
Interventions
Drug: Ivermectin
First Posted Date
2020-05-04
Last Posted Date
2020-05-04
Lead Sponsor
Max Healthcare Insititute Limited
Target Recruit Count
50
Registration Number
NCT04373824
Locations
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Max Super Speciality hospital, Saket (A unit of Devki Devi Foundation), New Delhi, Delhi, India

The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment

Phase 2
Recruiting
Conditions
COVID
Interventions
Drug: Ivermectin
First Posted Date
2020-04-17
Last Posted Date
2021-03-10
Lead Sponsor
Tanta University
Target Recruit Count
300
Registration Number
NCT04351347
Locations
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Tanta University, Tanta, Egypt

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

First Posted Date
2020-03-17
Last Posted Date
2024-10-09
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Target Recruit Count
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Registration Number
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Locations
🇨🇩

Centre de Recherche pour les Maladies Tropicales Negligees, Rethy, Ituri, Congo, The Democratic Republic of the

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Centre Suisse de Recherches Scientifiques en Coˆte d'Ivoire, Abidjan, Côte D'Ivoire

Rosacea and Ivermectin

Phase 2
Active, not recruiting
Conditions
Rosacea
Interventions
Drug: ivermectin
Device: GPSkin
Behavioral: digital interaction
First Posted Date
2020-02-19
Last Posted Date
2024-12-04
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
30
Registration Number
NCT04275999
Locations
🇺🇸

Wake Forest Health Sciences Dermatology, Winston-Salem, North Carolina, United States

Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis

First Posted Date
2019-08-14
Last Posted Date
2024-12-09
Lead Sponsor
Jennifer Keiser
Target Recruit Count
617
Registration Number
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Locations
🇱🇦

National Institute of Public Health, Vientiane, Lao People's Democratic Republic

Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients

First Posted Date
2019-08-01
Last Posted Date
2020-07-29
Lead Sponsor
Alejandro Krolewiecki
Target Recruit Count
176
Registration Number
NCT04041453
Locations
🇭🇳

Universidad Autónoma de Honduras, Tegucigalpa, Honduras

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IIET, Oran, Salta, Argentina

Repeat Ivermectin Mass Drug Administrations for MALaria Control II

Phase 3
Active, not recruiting
Conditions
Malaria
Interventions
Drug: Placebo oral tablet
Drug: Ivermectin
First Posted Date
2019-05-30
Last Posted Date
2024-01-11
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Brian Foy
Target Recruit Count
4124
Registration Number
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Locations
🇧🇫

Institut de Recherche en Sciences de la Sante, Diebougou, Sud-Ouest, Burkina Faso

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Phase 3
Active, not recruiting
Conditions
Onchocerciasis
Interventions
Drug: Moxidectin
Drug: Ivermectin
First Posted Date
2019-03-15
Last Posted Date
2024-10-09
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
323
Registration Number
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Locations
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Centre de Recherche pour les Maladies Tropicales Negligees, Rethy, Ituri, Congo, The Democratic Republic of the

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