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MEDICINES DEVELOPMENT FOR GLOBAL HEALTH LIMITED

🇦🇺Australia
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Efficacy and Safety Study of Moxidectin in Adults with Scabies

Phase 2
Active, not recruiting
Conditions
Scabies
Interventions
First Posted Date
2023-05-25
Last Posted Date
2024-10-29
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
200
Registration Number
NCT05875441
Locations
🇺🇸

LA Universal Research Center, Inc, Los Angeles, California, United States

🇺🇸

Evolution Clinical Trials, Miami, Florida, United States

🇺🇸

Medical Research of Westchester, Inc, Miami, Florida, United States

and more 6 locations

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

Phase 3
Completed
Conditions
Onchocerciasis
Interventions
First Posted Date
2020-03-17
Last Posted Date
2024-10-09
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
12997
Registration Number
NCT04311671
Locations
🇨🇩

Centre de Recherche pour les Maladies Tropicales Negligees, Rethy, Ituri, Congo, The Democratic Republic of the

🇨🇮

Centre Suisse de Recherches Scientifiques en Coˆte d'Ivoire, Abidjan, Côte D'Ivoire

A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years

Phase 1
Completed
Conditions
Onchocerciasis
Interventions
First Posted Date
2019-05-23
Last Posted Date
2022-12-15
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
36
Registration Number
NCT03962062
Locations
🇬🇭

University of Health and Allied Services School of Public Health, Hohoe, Volta Region, Ghana

Dose-finding Study of Moxidectin for Treatment of Scabies

Phase 2
Completed
Conditions
Scabies
Interventions
First Posted Date
2019-04-05
Last Posted Date
2023-09-22
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
22
Registration Number
NCT03905265
Locations
🇫🇷

Hopital Henri Mondor AP-HP, Créteil, France

🇦🇹

Medizinischen Universität Wien, Vienna, Austria

🇫🇷

CHU Nice Hopital Archet 2, Nice, France

and more 2 locations

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Phase 3
Active, not recruiting
Conditions
Onchocerciasis
Interventions
First Posted Date
2019-03-15
Last Posted Date
2024-10-09
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
323
Registration Number
NCT03876262
Locations
🇨🇩

Centre de Recherche pour les Maladies Tropicales Negligees, Rethy, Ituri, Congo, The Democratic Republic of the

Effect of a Single Oral Dose of Moxidectin on the Cardiac QT Interval of Healthy Volunteers

Phase 1
Completed
Conditions
QT Effects in Healthy Volunteers
Interventions
Other: Placebo
Drug: Moxidectin
First Posted Date
2017-01-06
Last Posted Date
2019-03-14
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
60
Registration Number
NCT03012828
Locations
🇺🇸

Spaulding Clinical, West Bend, Wisconsin, United States

A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People

Phase 1
Terminated
Conditions
HIV Infections
Interventions
Other: Dimethyl Sulfoxide
Biological: Opal-HIV-Gag(c) Low Dose
Biological: Opal-HIV-Gag(c) Medium dose
Biological: Opal-HIV-Gag(c) High dose
First Posted Date
2010-05-14
Last Posted Date
2018-03-22
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
22
Registration Number
NCT01123915
Locations
🇬🇧

St Stephen's Centre, Chelsea and Westminster Foundation Trust, London, United Kingdom

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

Phase 3
Completed
Conditions
Onchocerciasis
Interventions
First Posted Date
2008-11-14
Last Posted Date
2018-01-31
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
1497
Registration Number
NCT00790998
Locations
🇨🇩

Centre de Recherche en Maladies Tropicales de l'Ituri, Rethy, Congo, The Democratic Republic of the

🇱🇷

Liberian Institute for Biomedical Research Clinical Research Center, Bolahun, Lofa County, Liberia

🇨🇩

Centre de Recherche Clinique de Butembo - Université Catholique du Graben, Butembo, Congo, The Democratic Republic of the

and more 1 locations

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

First Posted Date
2006-03-09
Last Posted Date
2022-12-15
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
172
Registration Number
NCT00300768
Locations
🇬🇭

Onchocerciasis Chemotherapy Research Center, Hohoe, Volta Region, Ghana

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