MedPath

Itopride

Generic Name
Itopride
Drug Type
Small Molecule
Chemical Formula
C20H26N2O4
CAS Number
122898-67-3
Unique Ingredient Identifier
81BMQ80QRL
Background

Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.

Indication

Investigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous).

Associated Conditions
Abdominal Pain, Anorexia, Dyspepsia, Functional Dyspepsia, Gastroenteritis, Nausea, Nausea and vomiting, Vomiting, Abdominal bloating, Pyrosis, Stomach discomfort

Efficacy of Prokinetics With Split Dose of PEG in Morning Colonoscopic Bowel Preparation

Phase 3
Completed
Conditions
Colonoscopy
Bowel Preparation
Interventions
First Posted Date
2012-01-20
Last Posted Date
2012-04-03
Lead Sponsor
Inje University
Target Recruit Count
152
Registration Number
NCT01513096
Locations
🇰🇷

Haeundae Paik Hospital, Inje University School of Medicine, Busan, Korea, Republic of

Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation

Phase 2
Completed
Conditions
Irritable Bowel Syndrome
Interventions
First Posted Date
2009-12-07
Last Posted Date
2013-06-18
Lead Sponsor
Abbott
Target Recruit Count
268
Registration Number
NCT01027260
Locations
🇵🇰

Site Reference ID/Investigator# 21441, Karachi, Pakistan

🇵🇰

Site Reference ID/Investigator# 6130, Lahore, Pakistan

🇵🇰

Site Reference ID/Investigator# 5870, Karachi, Pakistan

and more 1 locations

Randomized Controlled Trial of Acupuncture for Functional Dyspepsia

Not Applicable
Completed
Conditions
Functional Dyspepsia
Interventions
Other: acupuncture
First Posted Date
2008-01-24
Last Posted Date
2011-11-09
Lead Sponsor
Chengdu University of Traditional Chinese Medicine
Target Recruit Count
720
Registration Number
NCT00599677
Locations
🇨🇳

Chengdu University of TCM, Chengdu, Sichuan, China

Efficacy and Safety of Itopride vs Placebo in Heartburn

Phase 3
Completed
Conditions
Heartburn
First Posted Date
2006-09-29
Last Posted Date
2017-02-09
Lead Sponsor
Forest Laboratories
Target Recruit Count
48
Registration Number
NCT00382577
Locations
🇺🇸

The Oklahoma Foundation for Digestive Research, Oklahoma City, Oklahoma, United States

Effects of Itopride on Gastric Motor and Sensory Functions in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2006-08-30
Last Posted Date
2017-02-09
Lead Sponsor
Forest Laboratories
Target Recruit Count
45
Registration Number
NCT00370110
Locations
🇺🇸

Mayo Clinic College of Medicine, Rochester, Minnesota, United States

Itopride Hydrochloride in Diabetes: Effects on Gastric Emptying and Glycemia

Phase 1
Completed
Conditions
Gastroparesis
Interventions
Other: Placebo
First Posted Date
2006-08-30
Last Posted Date
2017-02-09
Lead Sponsor
Forest Laboratories
Target Recruit Count
25
Registration Number
NCT00370084
Locations
🇦🇺

University of Adelaide, Department of Medicine, Adelaide, South Australia, Australia

A Study to Evaluate the Effect of a Medicine on Gastric Functions in Healthy Volunteers.

Phase 2
Completed
Conditions
Healthy Volunteers
First Posted Date
2006-03-29
Last Posted Date
2011-03-23
Lead Sponsor
Mayo Clinic
Target Recruit Count
45
Registration Number
NCT00308399
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Itopride in Functional Dyspepsia:a Dose Finding Study

Phase 2
Completed
Conditions
Functional Dyspepsia
First Posted Date
2006-01-04
Last Posted Date
2006-05-04
Lead Sponsor
Royal Adelaide Hospital
Target Recruit Count
500
Registration Number
NCT00272103
Locations
🇩🇪

University Hospital Essen, Essen, Germany

Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal

Phase 3
Completed
Conditions
Dyspepsia
First Posted Date
2005-06-01
Last Posted Date
2017-02-08
Lead Sponsor
Forest Laboratories
Target Recruit Count
500
Registration Number
NCT00112177
Locations
🇨🇦

Monique Giguère, Ph.D. - Programs Director, Mont-Saint-Hilaire, Quebec, Canada

Long-Term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia

Phase 3
Completed
Conditions
Dyspepsia
First Posted Date
2005-06-01
Last Posted Date
2017-02-08
Lead Sponsor
Forest Laboratories
Target Recruit Count
466
Registration Number
NCT00112203
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