MedPath

Ragifilimab

Generic Name
Ragifilimab

Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC

Phase 1
Recruiting
Conditions
Cancer of the Head and Neck
Interventions
First Posted Date
2020-07-14
Last Posted Date
2024-06-21
Lead Sponsor
Providence Health & Services
Target Recruit Count
56
Registration Number
NCT04470024
Locations
🇺🇸

Portland Providence Medical Center, Portland, Oregon, United States

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

Phase 2
Active, not recruiting
Conditions
Glioblastoma
Interventions
Drug: SRS
Procedure: Brain surgery
First Posted Date
2020-01-13
Last Posted Date
2025-02-25
Lead Sponsor
University of Pennsylvania
Target Recruit Count
39
Registration Number
NCT04225039
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

INCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic Malignancies

Phase 1
Terminated
Conditions
Advanced Malignancies
Metastatic Cancer
Interventions
First Posted Date
2017-09-11
Last Posted Date
2021-07-22
Lead Sponsor
Incyte Biosciences International Sàrl
Target Recruit Count
10
Registration Number
NCT03277352
Locations
🇺🇸

The Angeles Clinic and Research Institute, Los Angeles, California, United States

🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

Phase 1
Completed
Conditions
Advanced Malignancies
Metastatic Cancer
Interventions
First Posted Date
2017-04-24
Last Posted Date
2022-12-28
Lead Sponsor
Incyte Biosciences International Sàrl
Target Recruit Count
145
Registration Number
NCT03126110
Locations
🇺🇸

The Angeles Clinic and Research Institute, Los Angeles, California, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

🇺🇸

Washington University - Siteman Cancer Center, Saint Louis, Missouri, United States

and more 35 locations

Biomarker-based Study in R/M SCCHN

Phase 2
Active, not recruiting
Conditions
Carcinoma, Squamous Cell of Head and Neck
Interventions
First Posted Date
2017-03-23
Last Posted Date
2023-11-03
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
340
Registration Number
NCT03088059
Locations
🇧🇪

CHU Saint-Pierre-Site Porte de Hal, Brussels, Belgium

🇮🇹

IRCCS - Fondazione G. Pascale, Napoli, Italy

🇬🇧

Oxford University Hospitals NHS Trust - Churchill Hospital, Oxford, United Kingdom

and more 30 locations

A Study of INCAGN01876 in Participants With Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Advanced Malignancies
Metastatic Cancer
Interventions
First Posted Date
2016-03-03
Last Posted Date
2021-02-26
Lead Sponsor
Incyte Biosciences International Sàrl
Target Recruit Count
100
Registration Number
NCT02697591
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

MSK Westchester, Harrison, New York, United States

and more 5 locations
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