Cefepime
- Generic Name
- Cefepime
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N6O5S2
- CAS Number
- 88040-23-7
- Unique Ingredient Identifier
- 807PW4VQE3
- Background
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics. Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomo...
- Indication
Cefepime is indicated for the treatment of pneumonia caused by susceptible bacteria, and for empiric therapy for febrile neutropenic patients. Cefepime is also indicated for the treatment of uncomplicated and complicated urinary tract infections (including pyelonephritis), uncomplicated skin and skin structure infections, and complicated intra-abdominal infe...
- Associated Conditions
- Bacterial Infections, Complicated Intra-Abdominal Infections (cIAIs), Complicated Urinary Tract Infection, Febrile Neutropenia, Meningitis, Bacterial, Pyelonephritis, Severe Pneumonia, Uncomplicated Urinary Tract Infections, Moderate Pneumonia, Uncomplicated skin and subcutaneous tissue bacterial infections
- Associated Therapies
- -
An Efficacy and Safety of Flomoxef Versus Cefepime in the Treatment of Participants With Urinary Tract Infections
- First Posted Date
- 2014-11-26
- Last Posted Date
- 2017-10-27
- Lead Sponsor
- Takeda
- Target Recruit Count
- 13
- Registration Number
- NCT02302092
A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia
- First Posted Date
- 2010-04-26
- Last Posted Date
- 2014-07-15
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 7
- Registration Number
- NCT01110421
A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections
- First Posted Date
- 2010-04-26
- Last Posted Date
- 2014-07-15
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 41
- Registration Number
- NCT01110408
Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen
- First Posted Date
- 2008-02-07
- Last Posted Date
- 2008-02-07
- Lead Sponsor
- Javeriana University
- Target Recruit Count
- 30
- Registration Number
- NCT00609375
- Locations
- 🇨🇴
Fundacion San Carlos, Bogota, DC, Colombia
🇨🇴Hospital Santa Clara, Bogota, DC, Colombia
🇨🇴Hospital Universitario san Ignacio, Bogota, DC, Colombia
Cefepime vs. Ceftriaxone to Treat Nursing Home-Acquired Pneumonia
- First Posted Date
- 2006-07-31
- Last Posted Date
- 2007-10-31
- Lead Sponsor
- CPL Associates
- Target Recruit Count
- 69
- Registration Number
- NCT00358202
- Locations
- 🇺🇸
CPL Associates,LLC, Buffalo, New York, United States
Comparing Ciprofloxacin (CPFX) With Cefepime (CFPM) in Febrile Neutropenic Patients With Hematologic Diseases
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2018-06-26
- Lead Sponsor
- Center for Supporting Hematology-Oncology Trials
- Target Recruit Count
- 51
- Registration Number
- NCT00137787
- Locations
- 🇯🇵
Nagoya University Graduate School of Medicine, Nagoya, Japan
Drug Development Updates
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