MedPath

Emactuzumab

Generic Name
Emactuzumab
Drug Type
Biotech
CAS Number
1448221-67-7
Unique Ingredient Identifier
6FY6EI1X8R
Background

Emactuzumab is under investigation in clinical trial NCT01494688 (A Study of RO5509554 as Monotherapy and in Combination With Paclitaxel in Participants With Advanced Solid Tumors).

Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)

Phase 3
Recruiting
Conditions
TGCT
Interventions
Drug: Placebo
First Posted Date
2022-06-14
Last Posted Date
2025-04-18
Lead Sponsor
SynOx Therapeutics Limited
Target Recruit Count
128
Registration Number
NCT05417789
Locations
🇺🇸

NextGen Oncology, Beverly Hills, California, United States

🇺🇸

University of Kansas Cancer Center (Overland Park) - USOR, Overland Park, Kansas, United States

🇺🇸

Duke Cancer Center, Durham, North Carolina, United States

and more 40 locations

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

First Posted Date
2018-12-07
Last Posted Date
2025-05-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1000
Registration Number
NCT03768063
Locations
🇩🇪

Universitaets-Hautklinik Tuebingen, Tübingen, Germany

🇩🇪

Universitaettsklinikum Tübingen, Tübingen, Germany

🇩🇪

Universitätsklinik Tübingen, Tübingen, Germany

and more 83 locations

A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Phase 1
Withdrawn
Conditions
Lymphoma, Non-Hodgkin
Interventions
First Posted Date
2017-12-12
Last Posted Date
2018-04-05
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT03369964
Locations
🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Tennessee Oncology, Nashville, Tennessee, United States

A Study of Emactuzumab and RO7009789 Administered in Combination in Participants With Advanced Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2016-05-04
Last Posted Date
2018-05-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
38
Registration Number
NCT02760797
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

University Pennsylvania Hospital, Philadelphia, Pennsylvania, United States

🇫🇷

Institut Gustave Roussy; Sitep, VILLEJUIF Cedex, France

and more 3 locations

A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors

Phase 1
Completed
Conditions
Solid Cancers
Interventions
First Posted Date
2014-12-23
Last Posted Date
2020-08-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
221
Registration Number
NCT02323191
Locations
🇺🇸

Dana Farber - Harvard, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan-Kettering Cancer Center Breast & Imaging Center, New York, New York, United States

🇪🇸

Clinica Universitaria de Navarra; Servicio de Oncologia, Pamplona, Navarra, Spain

and more 9 locations

A Study of RO5509554 as Monotherapy and in Combination With Paclitaxel in Participants With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2011-12-19
Last Posted Date
2018-03-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
217
Registration Number
NCT01494688
Locations
🇫🇷

Centre Leon Berard; Departement Oncologie Medicale, Lyon, France

🇺🇸

Univ of Pennsylvania Med Ctr, Philadelphia, Pennsylvania, United States

🇫🇷

Institut Curie; Oncologie Medicale, Paris, France

and more 4 locations
© Copyright 2025. All Rights Reserved by MedPath