DeepMed Research

Mecobalamin

Generic Name: Mecobalamin

Drug Type: Small Molecule

Chemical Formula: C_₆₃H_₉₁CoN_₁₃O_₁₄P

CAS Number: 13422-55-4

Unique Ingredient Identifier: BR1SN1JS2W

Background: Not Available

Indication: Not Available

Associated Conditions: Vitamin B12 Deficiency

Associated Therapies: Nutritional supplementation

Clinical Trials

Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling

Phase 2

Not yet recruiting

Conditions: Diabetes Mellitus
Diabetic Retinopathy
Cognitive Impairment
Neurovascular Coupling

Interventions: Drug: hypoglycemic treatment
Drug: Tangshen'an Granules
Drug: Ginkgo Leaf Tablets
Drug: Mecobalamin Tablets
Drug: placebo

First Posted Date: 2025-02-06

Last Posted Date: 2025-02-06

Lead Sponsor: Hejiang Ye

Target Recruit Count: 160

Registration Number: NCT06813274

Locations: 🇨🇳
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
🇨🇳
Deyang Hospital Affiliated to Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, China
🇨🇳
Guangyuan North Sichuan Diabetes Specialty Hospital, Guangyuan, Sichuan, China

Mecobalamin Combined With Ceftriaxone Sodium in the Treatment of Sepsis Liver Injury

Phase 4

Not yet recruiting

Conditions: Sepsis
Liver Dysfunction

Interventions: Drug: Saline
Drug: Mecobalamin
Drug: Placebo
Drug: Ceftriaxone Sodium

First Posted Date: 2024-01-24

Last Posted Date: 2024-01-24

Lead Sponsor: Sichuan Provincial People's Hospital

Target Recruit Count: 40

Registration Number: NCT06220929

Locations: 🇨🇳
Sichuan Provincial People's Hospital, Chengdu, Sichuan, China

Effect of Ultrasound-guided Stellate Ganglion Block Combined With Facial Nerve and Glossopharyngeal Nerve Block on the Treatment of Sudden Deafness

Not Applicable

Recruiting

Conditions: Sudden Deafness

Interventions: Procedure: Stellate ganglion block
Procedure: Facial and glossopharyngeal nerve blocks
Drug: Mecobalamin Tablets

First Posted Date: 2022-11-21

Last Posted Date: 2022-11-21

Lead Sponsor: Zhuan Zhang

Target Recruit Count: 90

Registration Number: NCT05623384

Locations: 🇨🇳
the Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China

Effects of Epalrestat on Peripheral Neuropathy and Central Nervous System in Diabetic Patients

Phase 4

Conditions: Diabetes

Interventions: Drug: Epalrestat,Mecobalamin
Drug: Mecobalamin

First Posted Date: 2022-01-11

Last Posted Date: 2022-01-11

Lead Sponsor: Xiangya Hospital of Central South University

Target Recruit Count: 72

Registration Number: NCT05184049

Locations: 🇨🇳
Xiangya Hospital of Central South University, Changsha, Hunan, China

The Efficacy and Safety of Mecobalamin in the Prevention of Capecitabine Induced Hand Foot Syndrome

Phase 3

Active, not recruiting

Conditions: Hand-foot Syndrome

Interventions: Drug: placebo
Drug: Mecobalamin 5 MG Disintegrating Oral Tablet

First Posted Date: 2021-12-21

Last Posted Date: 2024-12-03

Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Target Recruit Count: 234

Registration Number: NCT05165069

Locations: 🇨🇳
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China

Evaluation of the Efficiacy of Mecobalamine in the Treatment of Long-term Pain in Women Diagnosed With Fibromyalgia

Phase 1

Completed

Conditions: Fibromyalgia

Interventions: Drug: Mecobalamin 5 MG

First Posted Date: 2021-08-17

Last Posted Date: 2024-12-18

Lead Sponsor: Linnaeus University

Target Recruit Count: 40

Registration Number: NCT05008042

Locations: 🇸🇪
Linnaeus University, Växjö, Kronoberg, Sweden

Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis

Not Applicable

Completed

Conditions: Peripheral Facial Palsy

Interventions: Procedure: Facial Nerve Block
Procedure: Stellate Ganglion Block
Drug: Mecobalamin Tablets

First Posted Date: 2021-03-16

Last Posted Date: 2022-11-22

Lead Sponsor: Zhuan Zhang

Target Recruit Count: 80

Registration Number: NCT04800666

Locations: 🇨🇳
the Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China

A Randomized Controlled Trial of Mecobalamin Injection and Tablet Treatment Efficacy on Mild to Moderate Diabetic Peripheral Neuropathy

Phase 2

Conditions: Diabetic Neuropathies

Interventions: Drug: methylcobalamin

First Posted Date: 2020-05-04

Last Posted Date: 2020-05-04

Lead Sponsor: Peking University Third Hospital

Target Recruit Count: 30

Registration Number: NCT04372316

Locations: 🇨🇳
Peking University Third Hospital, Beijing, China

Effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy

Not Applicable

Conditions: Diabetic Peripheral Neuropathy

Interventions: Device: Rotating Magnetic Therapy
Drug: Mecobalamin

First Posted Date: 2019-06-12

Last Posted Date: 2019-06-17

Lead Sponsor: Majianhua

Target Recruit Count: 200

Registration Number: NCT03983200

Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients

Phase 2

Completed

Conditions: Acute Lymphoblastic Leukaemia
Vincristine Induced Neurotoxicity

Interventions: Drug: Injection Mecobalamin
Drug: Normal saline
Drug: Tablet Pyridoxine hydrochlorid
Drug: Oral Placebo

First Posted Date: 2018-07-20

Last Posted Date: 2020-07-08

Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Target Recruit Count: 40

Registration Number: NCT03593304

Locations: 🇧🇩
Dhaka Medical College Hospital, Dhaka, Bangladesh
🇧🇩
Bangabandhu Sheikh Mujib Medical University, Dhaka, Shahbag, Bangladesh

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