Proguanil
- Generic Name
- Proguanil
- Brand Names
- Malarone
- Drug Type
- Small Molecule
- Chemical Formula
- C11H16ClN5
- CAS Number
- 500-92-5
- Unique Ingredient Identifier
- S61K3P7B2V
Overview
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
Background
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
Indication
For the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world.
Associated Conditions
- Malaria caused by Plasmodium falciparum
- Acute, uncomplicated Malaria caused by plasmodium falciparum
Clinical Trials
FDA Approved Products
Singapore Approved Products
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