Chlorothiazide

Generic Name
Chlorothiazide
Brand Names
Diuril
Drug Type
Small Molecule
Chemical Formula
C7H6ClN3O4S2
CAS Number
58-94-6
Unique Ingredient Identifier
77W477J15H
Background

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)

Indication

Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.

Associated Conditions
Edema, Hypertension
Associated Therapies
-

Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure

First Posted Date
2015-11-17
Last Posted Date
2019-11-08
Lead Sponsor
Vanderbilt University
Target Recruit Count
60
Registration Number
NCT02606253
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Treatment of Hypertension

First Posted Date
1999-10-28
Last Posted Date
2013-11-26
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000484

Study of Genotype and Phenotype Expression in Congenital Nephrogenic Diabetes Insipidus

First Posted Date
1999-10-19
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Registration Number
NCT00004360
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