地夫可特 (Emflaza)

概览

Deflazacort is a corticosteroid used to treat Duchenne muscular dystrophy.

作用机制

Deflazacort is a corticosteroid prodrug with an active metabolite, 21-deflazacort, which binds to the glucocorticoid receptor to exert anti-inflammatory and immunosuppressive effects on the body. The exact mechanism by which deflazacort exerts its therapeutic effects in patients with DMD is unknown but likely occurs via its anti-inflammatory activities.

适应症

⑴用于原发性肾上腺皮质功能减退、风湿病、胶原性疾病、皮肤病、变态反应性疾病、眼科疾病、暴发性和播散性肺结核、造血系统疾患、溃疡性结肠炎、特发性肾病综合征等。 ⑵用于治疗杜氏肌营养不良（DMD）。

• Duchenne Muscular Dystrophy (DMD)