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Flutamide

Generic Name
Flutamide
Brand Names
Eulexin
Drug Type
Small Molecule
Chemical Formula
C11H11F3N2O3
CAS Number
13311-84-7
Unique Ingredient Identifier
76W6J0943E
Background

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Indication

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Associated Conditions
Stage B2-C metastatic Carcinoma of the Prostate, Stage D2 metastatic Carcinoma of the Prostate

External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer

Phase 3
Terminated
Conditions
Prostate Cancer
Interventions
Procedure: Radiation Therapy
Behavioral: Questionnaire
First Posted Date
2006-10-17
Last Posted Date
2012-08-08
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
39
Registration Number
NCT00388804
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Effects of IAS in Men With Localized Biochemical Relapsed Prostate Cancer

Phase 2
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2005-09-22
Last Posted Date
2018-08-07
Lead Sponsor
University of Washington
Target Recruit Count
102
Registration Number
NCT00223665
Locations
🇺🇸

Seattle Cancer Care Alliance, Seattle, Washington, United States

Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer

Phase 2
Completed
Conditions
Stage III Prostate Cancer
Prostate Adenocarcinoma
Stage IV Prostate Cancer
Prostate Carcinoma
Recurrent Prostate Carcinoma
Interventions
First Posted Date
2005-09-15
Last Posted Date
2017-05-15
Lead Sponsor
Mayo Clinic
Target Recruit Count
112
Registration Number
NCT00170157
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Study of External Beam Radiation Therapy With and Without Hormonal Therapy to Treat Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
Radiation: External Beam Radiotherapy
First Posted Date
2005-06-28
Last Posted Date
2022-01-06
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
206
Registration Number
NCT00116220
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Triptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
Radiation: radiation therapy
First Posted Date
2005-03-04
Last Posted Date
2021-02-21
Lead Sponsor
UNICANCER
Target Recruit Count
378
Registration Number
NCT00104741
Locations
🇫🇷

Centre Hospital Regional Universitaire de Limoges, Limoges, France

🇫🇷

Centre Hospitalier Universitaire Henri Mondor, Creteil, France

🇫🇷

Clinique De Rochebelle, Ales, France

and more 28 locations

Flutamide, Suramin, and Hydrocortisone in Treating Patients With Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
First Posted Date
2004-08-24
Last Posted Date
2010-11-09
Lead Sponsor
Eastern Cooperative Oncology Group
Registration Number
NCT00002881
Locations
🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate

Phase 2
Completed
Conditions
Prostate Cancer
Interventions
Other: placebo
First Posted Date
2004-06-22
Last Posted Date
2016-07-13
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
63
Registration Number
NCT00006214
Locations
🇺🇸

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

🇺🇸

CCOP - Wichita, Wichita, Kansas, United States

🇺🇸

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

and more 20 locations

Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer

Phase 2
Completed
Conditions
Prostate Cancer
First Posted Date
2004-04-22
Last Posted Date
2023-08-18
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
180
Registration Number
NCT00002889
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 9 locations

Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
Radiation: radiation therapy
First Posted Date
2004-02-27
Last Posted Date
2018-06-14
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
2028
Registration Number
NCT00002597
Locations
🇺🇸

New York Medical College, Valhalla, New York, United States

🇺🇸

Wilkes Barre General Hospital, Wilkes-Barre, Pennsylvania, United States

🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

and more 236 locations

SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2004-02-06
Last Posted Date
2013-09-05
Lead Sponsor
University of Chicago
Target Recruit Count
3
Registration Number
NCT00026377
Locations
🇺🇸

Radiation Oncology, Chicago, Illinois, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

LaGrange Memorial Hospital, LaGrange, Illinois, United States

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