Flutamide

Generic Name
Flutamide
Brand Names
Eulexin
Drug Type
Small Molecule
Chemical Formula
C11H11F3N2O3
CAS Number
13311-84-7
Unique Ingredient Identifier
76W6J0943E
Background

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Indication

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Associated Conditions
Stage B2-C metastatic Carcinoma of the Prostate, Stage D2 metastatic Carcinoma of the Prostate
Associated Therapies
-

Triptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer

First Posted Date
2005-03-04
Last Posted Date
2021-02-21
Lead Sponsor
UNICANCER
Target Recruit Count
378
Registration Number
NCT00104741
Locations
🇫🇷

Centre Hospital Regional Universitaire de Limoges, Limoges, France

🇫🇷

Centre Hospitalier Universitaire Henri Mondor, Creteil, France

🇫🇷

Clinique De Rochebelle, Ales, France

and more 28 locations

Flutamide, Suramin, and Hydrocortisone in Treating Patients With Prostate Cancer

Phase 3
Completed
Conditions
First Posted Date
2004-08-24
Last Posted Date
2010-11-09
Lead Sponsor
Eastern Cooperative Oncology Group
Registration Number
NCT00002881
Locations
🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate

Phase 2
Completed
Conditions
Interventions
First Posted Date
2004-06-22
Last Posted Date
2016-07-13
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
63
Registration Number
NCT00006214
Locations
🇺🇸

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

🇺🇸

CCOP - Wichita, Wichita, Kansas, United States

🇺🇸

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

and more 20 locations

Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-04-22
Last Posted Date
2023-08-18
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
180
Registration Number
NCT00002889
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 9 locations

Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

First Posted Date
2004-02-27
Last Posted Date
2018-06-14
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
2028
Registration Number
NCT00002597
Locations
🇺🇸

New York Medical College, Valhalla, New York, United States

🇺🇸

Wilkes Barre General Hospital, Wilkes-Barre, Pennsylvania, United States

🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

and more 236 locations

SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

First Posted Date
2004-02-06
Last Posted Date
2013-09-05
Lead Sponsor
University of Chicago
Target Recruit Count
3
Registration Number
NCT00026377
Locations
🇺🇸

Radiation Oncology, Chicago, Illinois, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

LaGrange Memorial Hospital, LaGrange, Illinois, United States

Combination Hormone Therapy Followed by Radiation Therapy in Treating Patients With Prostate Cancer

Phase 3
Conditions
First Posted Date
2003-12-09
Last Posted Date
2016-07-21
Lead Sponsor
St. Luke's Hospital, Ireland
Target Recruit Count
276
Registration Number
NCT00003734
Locations
🇮🇪

Cork University Hospital, Cork, Ireland

🇮🇪

Letterkenny Hospital, Donnegal, Ireland

🇮🇪

St. Vincent's Hospital, Dublin, Ireland

and more 9 locations

Hormone Therapy in Treating Patients With Prostate Cancer

First Posted Date
2003-08-13
Last Posted Date
2016-07-04
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
101
Registration Number
NCT00003323
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

Marlene & Stewart Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, United States

🇺🇸

University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States

and more 40 locations

Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2003-07-15
Last Posted Date
2020-04-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
64
Registration Number
NCT00003645
Locations
🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

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