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Aminophylline

Generic Name
Aminophylline
Drug Type
Small Molecule
Chemical Formula
C16H24N10O4
CAS Number
317-34-0
Unique Ingredient Identifier
27Y3KJK423

Overview

Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.

Background

Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.

Indication

For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.

Associated Conditions

  • Acute Exacerbation of Chronic Bronchitis (AECB)
  • Asthma
  • Bronchial Asthma
  • Bronchospasm
  • Chronic Bronchitis
  • Exacerbation of asthma

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

AMINOPHYLLINE INJECTION 0.25 g/10 ml
Manufacturer:ATLANTIC LABORATORIES CORPN LTD
Form:INJECTION
Strength:0.25 g/10 ml
Online:Yes
Approved: 1989/06/21
Approval:SIN03471P

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