Aminophylline

Generic Name
Aminophylline
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C16H24N10O4
CAS Number
317-34-0
Unique Ingredient Identifier
27Y3KJK423
Background

Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, ch...

Indication

For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Asthma, Bronchial Asthma, Bronchospasm, Chronic Bronchitis, Exacerbation of asthma
Associated Therapies
-

Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-11-22
Last Posted Date
2015-06-08
Lead Sponsor
Stanford University
Target Recruit Count
144
Registration Number
NCT01245595
Locations
🇺🇸

Lucile Packard Childrens' Hospital, Palo Alto, California, United States

Study of BCG + Aminophylline Toxicity When Used in the Treatment of Bladder Cancer

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-11-15
Last Posted Date
2014-04-14
Lead Sponsor
University of Virginia
Target Recruit Count
3
Registration Number
NCT01240824
Locations
🇺🇸

University of Virginia Urology Department, Charlottesville, Virginia, United States

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