Nepafenac
- Generic Name
- Nepafenac
- Brand Names
- Ilevro, Nevanac
- Drug Type
- Small Molecule
- Chemical Formula
- C15H14N2O2
- CAS Number
- 78281-72-8
- Unique Ingredient Identifier
- 0J9L7J6V8C
- Background
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
- Indication
For the treatment of pain and inflammation associated with cataract surgery.
- Associated Conditions
- Inflammation, Pain
A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification
- Conditions
- Cataracts
- Interventions
- First Posted Date
- 2009-10-27
- Last Posted Date
- 2011-10-03
- Lead Sponsor
- Frank A. Bucci, Jr., M.D.
- Target Recruit Count
- 126
- Registration Number
- NCT01001806
- Locations
- 🇺🇸
Bucci Laser Vision Institute, Wilkes-Barre, Pennsylvania, United States
Macular Edema Incidence/Severity Reduction With Nevanac
- Conditions
- Diabetic Retinopathy
- Interventions
- First Posted Date
- 2009-07-14
- Last Posted Date
- 2012-10-23
- Lead Sponsor
- Alcon Research
- Target Recruit Count
- 175
- Registration Number
- NCT00939276
- Locations
- 🇺🇸
Contact Alcon Call Center For Trial Locations, Fort Worth, Texas, United States
Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema
- Conditions
- Diabetic RetinopathyMacular Edema
- Interventions
- First Posted Date
- 2009-05-13
- Last Posted Date
- 2015-03-20
- Lead Sponsor
- Hospital Juarez de Mexico
- Target Recruit Count
- 84
- Registration Number
- NCT00900887
- Locations
- 🇲🇽
Virgilio Lima Gomez, Mexico, Distrito Federal, Mexico
Comparison of Pain Sensation During Single Use of Two Topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- First Posted Date
- 2009-03-25
- Last Posted Date
- 2009-03-26
- Lead Sponsor
- Santa Casa de Misericordia de Santos
- Target Recruit Count
- 40
- Registration Number
- NCT00869219
- Locations
- 🇧🇷
Santa Casa de Misericordia de Santos, Santos, Sao Paulo, Brazil
Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in Facetectomies
- Conditions
- Cataract
- Interventions
- First Posted Date
- 2009-03-19
- Last Posted Date
- 2011-05-24
- Lead Sponsor
- Clinica Oftamologica Zona Sul
- Target Recruit Count
- 30
- Registration Number
- NCT00865540
- Locations
- 🇧🇷
Clínica Oftalmológica Zona Sul, Recife, Pernambuco, Brazil
Evaluation of Comfort With Xibrom (Bromfenac Ophthalmic Solution)0.09% and Nevanac (Nepafenac Ophthalmic Suspension) 0.1% Following Selective Laser Trabeculoplasty (SLT)
- First Posted Date
- 2009-01-26
- Last Posted Date
- 2009-06-10
- Lead Sponsor
- Bp Consulting, Inc
- Target Recruit Count
- 25
- Registration Number
- NCT00828477
- Locations
- 🇺🇸
Coburn-Kleinfeldt Eye Clinic, 3340 6 mile Rd Livonia, Michigan, United States
Role of Nepafenac in Reducing Macular Volume After Epiretinal Membrane Surgery
- First Posted Date
- 2009-01-08
- Last Posted Date
- 2015-08-14
- Lead Sponsor
- Alcon Research
- Target Recruit Count
- 40
- Registration Number
- NCT00818844
- Locations
- 🇺🇸
Dan Miller, Cincinnati, Ohio, United States
Effect of Topical Nepafenac in Macular Thickening Related to Pan-retinal Photocoagulation
- Conditions
- Macular ThickeningMacular Edema
- Interventions
- Other: Lubricant
- First Posted Date
- 2008-12-04
- Last Posted Date
- 2024-05-30
- Lead Sponsor
- Asociación para Evitar la Ceguera en México
- Target Recruit Count
- 50
- Registration Number
- NCT00801905
- Locations
- 🇲🇽
Asociacion para Evitar la Ceguera en Mexico I.A.P., Mexico City, Mexico
🇲🇽Asociación Para Evitar la Ceguera en México I.A.P., Mexico City, Mexico
A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients
- Conditions
- Macular Edema
- Interventions
- Other: Nepafenac ophthalmic suspension vehicle
- First Posted Date
- 2008-10-31
- Last Posted Date
- 2012-10-26
- Lead Sponsor
- Alcon Research
- Target Recruit Count
- 263
- Registration Number
- NCT00782717
Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
- First Posted Date
- 2007-06-29
- Last Posted Date
- 2011-07-12
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 82
- Registration Number
- NCT00494494
- Locations
- 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Drug Development Updates
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