Gonadorelin
- Generic Name
- Gonadorelin
- Brand Names
- Lutrepulse
- Drug Type
- Small Molecule
- Chemical Formula
- C55H75N17O13
- CAS Number
- 33515-09-2
- Unique Ingredient Identifier
- 9O7312W37G
- Background
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
- Indication
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
- Associated Therapies
- Ovulation induction therapy
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients
- Conditions
- Endometrioma
- Interventions
- Procedure: endometrioma aspirationProcedure: standard long stimulation protocol
- First Posted Date
- 2016-04-14
- Last Posted Date
- 2018-07-31
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 88
- Registration Number
- NCT02737800
- Locations
- 🇪🇬
Kasrelaini Hospital, Giza, Egypt
Cryopreserved-thawed Embryo Transfer With or Without Gonadotropin Releasing Hormone Agonist
- Conditions
- Infertility
- Interventions
- Procedure: Embryo transferProcedure: Serum Estradiol and Progesterone levelsDrug: External Estradiol
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2018-05-17
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 310
- Registration Number
- NCT02736032
- Locations
- 🇪🇬
Nile IVF center, Giza, Egypt
🇪🇬IVF centre, Obstetrics and Gynaecology Department, Cairo University Hospitals (Kasr EL Aini), Cairo, Egypt
🇪🇬Kamal Shaeer center of infertility, Giza, Egypt
Efficacy of Pulsatile GnRH Therapy on Male Patients With Pituitary Stalk Interruption Syndrome
- Conditions
- Hypogonadotropic Hypogonadism
- Interventions
- First Posted Date
- 2016-03-10
- Last Posted Date
- 2016-03-10
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT02705014
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China
Reprometabolic Syndrome Mediates Subfertility in Obesity
- Conditions
- ObesityInfertilityHypogonadotropic HypogonadotropismHyperinsulinemia
- Interventions
- Procedure: Hyperinsulinemic Euglycemic Clamp
- First Posted Date
- 2016-01-12
- Last Posted Date
- 2025-05-14
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 84
- Registration Number
- NCT02653092
- Locations
- 🇺🇸
University of Colorado Denver, Aurora, Colorado, United States
Poor Ovarian Stimulation Response in In Vitro Fertilization (IVF) Program
- Conditions
- Infertility
- Interventions
- Drug: Human menopausal gonadotrophin (HMG)Drug: Human chorionic gonadotrophin (hCG)
- First Posted Date
- 2015-12-29
- Last Posted Date
- 2015-12-29
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 216
- Registration Number
- NCT02640976
A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation
- Conditions
- Polycystic Ovary Syndrome
- Interventions
- First Posted Date
- 2015-11-18
- Last Posted Date
- 2018-06-28
- Lead Sponsor
- Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 1064
- Registration Number
- NCT02607293
- Locations
- 🇩🇪
Merck KGaA Communication Center, Darmstadt, Germany
An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
- Conditions
- Prostatic Neoplasms
- Interventions
- Radiation: 74-80 Grays (units of radiation)
- First Posted Date
- 2015-08-24
- Last Posted Date
- 2025-04-04
- Lead Sponsor
- Aragon Pharmaceuticals, Inc.
- Target Recruit Count
- 1503
- Registration Number
- NCT02531516
Cabergoline Versus GnRH Antagonist Rescue and Cabergoline in the Prevention of Ovarian Hyperstimulation Syndrome
- First Posted Date
- 2015-06-03
- Last Posted Date
- 2015-11-17
- Lead Sponsor
- Aljazeera Hospital
- Target Recruit Count
- 236
- Registration Number
- NCT02461875
- Locations
- 🇪🇬
Aljazeera( Al Gazeera) hospital, Giza, Egypt
Endometrial Volume and Sub-endometrial Vascularity as Predictors of In-vitro Fertilization Success
- Conditions
- Reproductive Techniques, Assisted
- Interventions
- Other: 3 D ultrasound and Doppler examination
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2018-01-03
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 82
- Registration Number
- NCT02381821
IVF Treatment in Women With Immature Oocytes in Previous Cycle
- Conditions
- Infertility
- Interventions
- Drug: high dose hCG 500 mcg
- First Posted Date
- 2015-02-23
- Last Posted Date
- 2022-06-24
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT02368964
- Locations
- 🇮🇱
Sheba Medical Center, Ramat Gan, Israel
Drug Development Updates
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