Salsalate

Generic Name
Salsalate
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C14H10O5
CAS Number
552-94-3
Unique Ingredient Identifier
V9MO595C9I
Background

Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established. In...

Indication

For relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.

Associated Conditions
-
Associated Therapies
-

Salsalate in Patients Mild to Moderate Alzheimer's Disease

Phase 1
Conditions
Interventions
First Posted Date
2017-09-11
Last Posted Date
2021-04-01
Lead Sponsor
Adam Boxer
Target Recruit Count
40
Registration Number
NCT03277573
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

🇺🇸

University of California, San Diego, San Diego, California, United States

Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-07-25
Last Posted Date
2024-06-25
Lead Sponsor
University of Illinois at Chicago
Target Recruit Count
60
Registration Number
NCT03229408
Locations
🇺🇸

Frank González, Chicago, Illinois, United States

The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease

First Posted Date
2017-07-19
Last Posted Date
2019-08-22
Lead Sponsor
Korea University Guro Hospital
Target Recruit Count
34
Registration Number
NCT03222206
Locations
🇰🇷

Korea University Guro Hospital, Seoul, Korea, Republic of

Targeting Inflammation With Salsalate in Type 1 Diabetes Neuropathy

First Posted Date
2016-10-18
Last Posted Date
2023-07-10
Lead Sponsor
University of Michigan
Target Recruit Count
61
Registration Number
NCT02936843
Locations
🇺🇸

University of Michigan Health System, Ann Arbor, Michigan, United States

🇺🇸

Veterans Administration Ann Arbor Health Center, Ann Arbor, Michigan, United States

A 6 Month, Open-Label, Pilot Futility Clinical Trial of Oral Salsalate for Progressive Supranuclear Palsy

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-04-21
Last Posted Date
2021-04-01
Lead Sponsor
Adam Boxer
Target Recruit Count
10
Registration Number
NCT02422485
Locations
🇺🇸

OHSU Parkinson Center & Movement Disorder Program, Portland, Oregon, United States

🇺🇸

University of California, San Francisco, San Francisco, California, United States

Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)

First Posted Date
2015-04-02
Last Posted Date
2019-01-08
Lead Sponsor
Emory University
Target Recruit Count
36
Registration Number
NCT02406586
Locations
🇺🇸

Grady Memorial Hospital, Atlanta, Georgia, United States

Beneficial Effect of Salicylates: Insulin Action, Secretion or Clearance?

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2013-12-11
Last Posted Date
2016-05-05
Lead Sponsor
Stanford University
Target Recruit Count
41
Registration Number
NCT02007577
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Inflammation Inhibition in Prediabetic Humans

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2013-11-06
Last Posted Date
2023-09-11
Lead Sponsor
Gary L. Pierce
Target Recruit Count
21
Registration Number
NCT01977417
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

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