Salsalate

Generic Name
Salsalate
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C14H10O5
CAS Number
552-94-3
Unique Ingredient Identifier
V9MO595C9I
Background

Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established. In...

Indication

For relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.

Associated Conditions
-
Associated Therapies
-

Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-11-06
Last Posted Date
2017-03-10
Lead Sponsor
Boston University
Target Recruit Count
60
Registration Number
NCT00553995
Locations
🇺🇸

Boston University School of Medicine, Boston, Massachusetts, United States

Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-10-26
Last Posted Date
2019-04-08
Lead Sponsor
Joslin Diabetes Center
Target Recruit Count
277
Registration Number
NCT00392678
Locations
🇺🇸

Endocrine Clinical Research, Winter Park, Florida, United States

🇺🇸

Kaiser Permanente, Atlanta, Georgia, United States

🇺🇸

Emory School of Medicine, Atlanta, Georgia, United States

and more 13 locations

The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers

Phase 4
Completed
Conditions
Interventions
First Posted Date
2006-06-21
Last Posted Date
2013-03-06
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
54
Registration Number
NCT00339833
Locations
🇺🇸

NIDDK, Phoenix, Phoenix, Arizona, United States

Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk

First Posted Date
2006-05-29
Last Posted Date
2020-01-21
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
71
Registration Number
NCT00330733
Locations
🇺🇸

Carl T. Hayden VA Medical Center, Phoenix, Arizona, United States

The Study of Inflammation on Blood Glucose Levels in Obese People

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-11-24
Last Posted Date
2018-02-15
Lead Sponsor
Joslin Diabetes Center
Target Recruit Count
20
Registration Number
NCT00258115
Locations
🇺🇸

Joslin Diabetes Center, Boston, Massachusetts, United States

Effect of Salicylate on Glucose Metabolism in Insulin Resistance States

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-11-24
Last Posted Date
2019-04-30
Lead Sponsor
Joslin Diabetes Center
Target Recruit Count
17
Registration Number
NCT00258128
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