Cannabidiol

Generic Name
Cannabidiol
Brand Names
Epidiolex, Sativex, Epidyolex
Drug Type
Small Molecule
Chemical Formula
C21H30O2
CAS Number
13956-29-1
Unique Ingredient Identifier
19GBJ60SN5
Background

Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact medical implications are currently being investig...

Indication

When used in combination with delta-9-tetrahydrocannabinol as the product Sativex, cannabidiol was given a standard marketing authorization (ie. a Notice of Compliance (NOC)) by Health Canada for the following indications:
...

Associated Conditions
Multiple Sclerosis, Seizures, Severe Pain, Moderate Pain
Associated Therapies
-
Clinical Trials
Related News

CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF

Phase 4
Withdrawn
Conditions
Ankle Fractures
Tibia Fracture
Interventions
Drug: Placebo
Drug: CBD
First Posted Date
2021-02-24
Last Posted Date
2022-01-28
Lead Sponsor
NYU Langone Health
Registration Number
NCT04768478
Locations
๐Ÿ‡บ๐Ÿ‡ธ

NYU Langone Orthopedic Hospital, New York, New York, United States

CBD for Chronic Radicular Pain on Chronic Opioid Therapy (COT)

Phase 1
Completed
Conditions
Radiculopathy
Interventions
Drug: Cannabidiol
Drug: Placebo
First Posted Date
2021-02-18
Last Posted Date
2024-07-15
Lead Sponsor
NYU Langone Health
Target Recruit Count
14
Registration Number
NCT04760613
Locations
๐Ÿ‡บ๐Ÿ‡ธ

NYU Langone Health, New York, New York, United States

Cannabidiol for Bilateral Total Knee Arthroplasty

First Posted Date
2021-02-11
Last Posted Date
2024-10-26
Lead Sponsor
Hospital for Special Surgery, New York
Target Recruit Count
36
Registration Number
NCT04749628
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Hospital for Special Surgery, New York, New York, United States

The Pharmacokinetics and Pharmacodynamics of Hemp-based Topical Cannabinoid Products

Phase 1
Completed
Conditions
Cannabis
Drug Effect
Interventions
Drug: CBD
Drug: Placebo
Drug: THC
First Posted Date
2021-02-05
Last Posted Date
2023-03-10
Lead Sponsor
Johns Hopkins University
Target Recruit Count
47
Registration Number
NCT04741477
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States

Cannabidiol and Autonomic Function at Rest

Early Phase 1
Completed
Conditions
Healthy
Interventions
Drug: cannabidiol
Drug: Placebo
First Posted Date
2021-02-01
Last Posted Date
2023-05-15
Lead Sponsor
Castleton University
Target Recruit Count
18
Registration Number
NCT04731779
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Castleton University, Jeffords Science Building, Castleton, Vermont, United States

Cannabidiol Treatment for Severe and Critical Coronavirus (COVID-19) Pulmonary Infection

Phase 1
Conditions
COVID-19
Interventions
Drug: Cannabidiol
First Posted Date
2021-01-29
Last Posted Date
2021-01-29
Lead Sponsor
Rabin Medical Center
Target Recruit Count
40
Registration Number
NCT04731116
Locations
๐Ÿ‡ฎ๐Ÿ‡ฑ

Rabin Medical Center, Petach Tikva, Israel

Cannabidiol for Fibromyalgia (The CANNFIB Trial)

Phase 3
Completed
Conditions
Fibromyalgia
Interventions
Drug: Placebo
Drug: Cannabidiol
First Posted Date
2021-01-28
Last Posted Date
2024-03-25
Lead Sponsor
Marius Henriksen
Target Recruit Count
200
Registration Number
NCT04729179
Locations
๐Ÿ‡ฉ๐Ÿ‡ฐ

The Parker Institute, Frederiksberg Hospital, Copenhagen, Denmark

The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management

First Posted Date
2021-01-28
Last Posted Date
2021-08-06
Lead Sponsor
Advanced Pain and Rehab Specialists
Target Recruit Count
30
Registration Number
NCT04729244
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Advanced Pain and Rehab Specialists, Hermitage, Pennsylvania, United States

Synthetic CBD as a Therapy for COVID-19

Phase 1
Conditions
Covid19
CBD
Interventions
Drug: Placebo
Drug: CBD
First Posted Date
2020-12-28
Last Posted Date
2021-09-28
Lead Sponsor
Sheba Medical Center
Target Recruit Count
50
Registration Number
NCT04686539
Locations
๐Ÿ‡ฎ๐Ÿ‡ฑ

Sheba Medical Center, Tel Hashomer, Ramat Gan, Tel Aviv, Israel

Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet

First Posted Date
2020-12-22
Last Posted Date
2021-02-02
Lead Sponsor
Pure Green
Target Recruit Count
50
Registration Number
NCT04679545
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Pure Green Pharmaceuticals, Bloomfield Township, Michigan, United States

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