Cannabidiol

Generic Name
Cannabidiol
Brand Names
Epidiolex, Sativex, Epidyolex
Drug Type
Small Molecule
Chemical Formula
C21H30O2
CAS Number
13956-29-1
Unique Ingredient Identifier
19GBJ60SN5
Background

Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact medical implications are currently being investig...

Indication

When used in combination with delta-9-tetrahydrocannabinol as the product Sativex, cannabidiol was given a standard marketing authorization (ie. a Notice of Compliance (NOC)) by Health Canada for the following indications:
...

Associated Conditions
Multiple Sclerosis, Seizures, Severe Pain, Moderate Pain
Associated Therapies
-

Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-06-25
Last Posted Date
2023-05-25
Lead Sponsor
Anne Comi, MD
Target Recruit Count
11
Registration Number
NCT04447846
Locations
🇺🇸

Kennedy Krieger Institute, Baltimore, Maryland, United States

Study to Evaluate the Safety, Tolerability and Efficacy of Cannabidiol (CBD) as a Steroid-sparing Therapy in Chronic Spontaneous Urticaria (CSU) Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-06-19
Last Posted Date
2024-04-18
Lead Sponsor
Stero Biotechs Ltd.
Target Recruit Count
15
Registration Number
NCT04439955
Locations
🇮🇱

Meir Medical Center, Kfar Saba, Israel

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-05-14
Last Posted Date
2023-01-18
Lead Sponsor
Mayo Clinic
Target Recruit Count
90
Registration Number
NCT04387617
Locations
🇺🇸

Mayo Clinic in Arizona, Phoenix, Arizona, United States

A Clinical Trial of a Hemp-Derived Cannabidiol Product for Anxiety

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2020-02-27
Last Posted Date
2024-08-27
Lead Sponsor
Mclean Hospital
Target Recruit Count
15
Registration Number
NCT04286594
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-02-25
Last Posted Date
2024-08-07
Lead Sponsor
Johns Hopkins University
Target Recruit Count
75
Registration Number
NCT04283019
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients

First Posted Date
2020-02-17
Last Posted Date
2022-05-02
Lead Sponsor
University of Tennessee
Target Recruit Count
68
Registration Number
NCT04271917
Locations
🇺🇸

University of Tennessee Health Science Center, Memphis, Tennessee, United States

Cannabidiol for Anxiety

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2020-02-13
Last Posted Date
2020-12-19
Lead Sponsor
CB2 Insights
Registration Number
NCT04267679

Oral Cannabidiol for Opioid Withdrawal

First Posted Date
2020-01-23
Last Posted Date
2023-08-29
Lead Sponsor
Johns Hopkins University
Target Recruit Count
3
Registration Number
NCT04238754
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers

Early Phase 1
Terminated
Conditions
Interventions
First Posted Date
2020-01-18
Last Posted Date
2024-05-10
Lead Sponsor
University of California, San Diego
Target Recruit Count
19
Registration Number
NCT04231643
Locations
🇺🇸

UC San Diego Medical Center, San Diego, California, United States

Cannabidiol (CBD) for the Treatment of Alcohol Withdrawal

First Posted Date
2019-12-19
Last Posted Date
2020-01-09
Lead Sponsor
South West Sydney Local Health District
Target Recruit Count
52
Registration Number
NCT04205682
Locations
🇦🇺

Sydney and Sydney Eye Hospital, Sydney, New South Wales, Australia

🇦🇺

Royal Prince Alfred Hospital, Sydney, New South Wales, Australia

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