Cannabidiol

Generic Name
Cannabidiol
Brand Names
Epidiolex, Sativex, Epidyolex
Drug Type
Small Molecule
Chemical Formula
C21H30O2
CAS Number
13956-29-1
Unique Ingredient Identifier
19GBJ60SN5
Background

Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact medical implications are currently being investig...

Indication

When used in combination with delta-9-tetrahydrocannabinol as the product Sativex, cannabidiol was given a standard marketing authorization (ie. a Notice of Compliance (NOC)) by Health Canada for the following indications:
...

Associated Conditions
Multiple Sclerosis, Seizures, Severe Pain, Moderate Pain
Associated Therapies
-

CBD Treatment in Hand Osteoarthritis and Psoriatic Arthritis.

First Posted Date
2018-10-03
Last Posted Date
2021-07-07
Lead Sponsor
Aalborg University Hospital
Target Recruit Count
136
Registration Number
NCT03693833
Locations
🇩🇰

Department of Rheumatology Aalborg Universityhospital North, Aalborg, Denmark

Cannabidiol for Drug Resistant Pediatric Epilepsy (Expanded Access Use)

First Posted Date
2018-09-18
Last Posted Date
2024-05-09
Lead Sponsor
John
Registration Number
NCT03676049
Locations
🇺🇸

University of Mississippi Medical Center, Jackson, Mississippi, United States

Cannabis Oil for Chronic Non-Cancer Pain Treatment

First Posted Date
2018-08-17
Last Posted Date
2018-11-13
Lead Sponsor
Hamilton Health Sciences Corporation
Target Recruit Count
309
Registration Number
NCT03635593
Locations
🇨🇦

Michael G. DeGroote Pain Clinic, Hamilton, Ontario, Canada

🇨🇦

Toronto Poly Clinic, Toronto, Ontario, Canada

Cannabidiol in Patients With Heart Failure Failure in AHA/ACC Stages A-C

Phase 1
Conditions
Interventions
First Posted Date
2018-08-16
Last Posted Date
2020-08-05
Lead Sponsor
Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud
Target Recruit Count
20
Registration Number
NCT03634189

A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-07-10
Last Posted Date
2024-07-23
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
74
Registration Number
NCT03582137
Locations
🇺🇸

University of Colorado hospital, Aurora, Colorado, United States

Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-05-25
Last Posted Date
2024-03-05
Lead Sponsor
King's College London
Target Recruit Count
38
Registration Number
NCT03537950
Locations
🇬🇧

King's College London, London, United Kingdom

Cannabidiol and Prolonged Exposure

First Posted Date
2018-05-08
Last Posted Date
2024-10-07
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
136
Registration Number
NCT03518801
Locations
🇺🇸

VA San Diego Healthcare System, San Diego, CA, San Diego, California, United States

Cannabidiol - an in Vivo Innovative Drug Delivery Study

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2018-03-20
Last Posted Date
2020-07-01
Lead Sponsor
Central Institute of Mental Health, Mannheim
Target Recruit Count
8
Registration Number
NCT03471559
Locations
🇩🇪

Department I of Pharmacology, University of Cologne, Cologne, Germany

Cannabidiol Usage as an Adjunct Therapy for Crohn's Disease

First Posted Date
2018-03-16
Last Posted Date
2020-03-25
Lead Sponsor
University of Illinois at Chicago
Registration Number
NCT03467620
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