Fentanyl

Generic Name
Fentanyl
Brand Names
Abstral, Actiq, Duragesic, Effentora, Fentora, Instanyl, Lazanda, Sublimaze, Subsys, PecFent
Drug Type
Small Molecule
Chemical Formula
C22H28N2O
CAS Number
437-38-7
Unique Ingredient Identifier
UF599785JZ
Background

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia. Fentanyl is related to other opioids like morphine and oxycodone.
...

Indication

Fentanyl intravenous or intramuscular injections are indicated for short term analgesia during induction, maintenance, and recovery from general or regional anesthesia. These injections are also used with a neuroleptic for premedication, induction, and as an adjunct to maintenance of anesthesia. Finally, fentanyl intravenous or intramuscular injections are u...

Associated Conditions
Cancer Related Pain (Breakthrough Pain), Severe, Chronic Pain
Associated Therapies
Anesthetic premedication therapy, Anesthetics Agent, General Anesthesia, Induction of anesthesia therapy, Maintenance of anesthesia therapy, Regional Anesthesia therapy
Clinical Trials
Related News

Continuous Infusion of Fentanyl in Preterm on MV

First Posted Date
2007-12-12
Last Posted Date
2011-10-12
Lead Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Target Recruit Count
128
Registration Number
NCT00571636
Locations
🇮🇹

St'Orsola-Malpighi General Hospital, Bologna, BO, Italy

Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

First Posted Date
2007-11-22
Last Posted Date
2011-08-08
Lead Sponsor
Asker & Baerum Hospital
Target Recruit Count
102
Registration Number
NCT00562627
Locations
🇳🇴

Asker and Baerum Hospital, Rud, Norway

Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery

First Posted Date
2007-10-11
Last Posted Date
2015-04-13
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
89
Registration Number
NCT00542542
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy

First Posted Date
2007-09-10
Last Posted Date
2012-01-26
Lead Sponsor
Preben Kjolhede
Target Recruit Count
180
Registration Number
NCT00527332
Locations
🇸🇪

Värnamo Hospital, Värnamo, Sweden

🇸🇪

Eksjö Hospital, Eksjö, Sweden

🇸🇪

Ryhov Hospital, Jönköping, Sweden

and more 2 locations

Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy

Phase 3
Completed
Conditions
Obstructive Sleep Apnea
Interventions
Drug: fentanyl
Drug: dexmedetomidine
First Posted Date
2007-05-01
Last Posted Date
2016-12-05
Lead Sponsor
University of Medicine and Dentistry of New Jersey
Target Recruit Count
122
Registration Number
NCT00468052
Locations
🇺🇸

UMDNJ University Hospital, Newark, New Jersey, United States

Neuronal Mechanisms of Sensory Processing During General Anesthesia

Not Applicable
Conditions
General Anesthesia
First Posted Date
2007-02-13
Last Posted Date
2010-07-30
Lead Sponsor
Ludwig-Maximilians - University of Munich
Target Recruit Count
768
Registration Number
NCT00434382
Locations
🇩🇪

Klinik fuer Anaesthesiologie am Universitätsklinikum Schleswig Holstein, Campus Luebeck, Lubeck, Germany

🇩🇪

Klinik fuer Anaesthesiologie der Ludwigs-Maximilians-Universitaet Muenchen, Munich, Germany

🇩🇪

Krankenhaus Friedrichshafen, Friedrichshafen, Germany

and more 1 locations

Rapip Study: Clinical Trial on Remifentanyl for Analgesia and Sedation of Ventilated Neonates and Infants

Phase 3
Completed
Conditions
Mechanical Ventilation
Interventions
Drug: Remifentanyl
Drug: Fentanyl
First Posted Date
2007-01-08
Last Posted Date
2010-06-25
Lead Sponsor
University of Cologne
Target Recruit Count
24
Registration Number
NCT00419601
Locations
🇩🇪

Clinic for Paediatrics, University of Cologne Kerpener Str. 62, Cologne, Germany

Intranasal Fentanyl Versus Placebo for Catheterization During a Voiding Cystourethrogram in Children

Phase 3
Completed
Conditions
Pain
Interventions
Drug: Sterile water
Drug: Fentanyl
First Posted Date
2006-11-30
Last Posted Date
2010-12-13
Lead Sponsor
The Hospital for Sick Children
Target Recruit Count
64
Registration Number
NCT00405444
Locations
🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

Acute Neurological ICU Sedation Trial (ANIST)

First Posted Date
2006-10-20
Last Posted Date
2019-05-16
Lead Sponsor
Johns Hopkins University
Target Recruit Count
35
Registration Number
NCT00390871
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

Efficacy and Safety of Intranasal Fentanyl in the Treatment of Breakthrough Pain (FT-018-IM)

Phase 3
Completed
Conditions
Cancer
First Posted Date
2006-08-10
Last Posted Date
2012-05-07
Lead Sponsor
Nycomed
Target Recruit Count
100
Registration Number
NCT00362583
Locations
🇩🇰

Nycomed, Roskilde, Denmark

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