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Botulinum toxin E

Generic Name
Botulinum toxin E

A Study to Assess the Adverse Events of Intramuscular Injections of AGN-151586 and OnabotulinumtoxinA in Adult Participants for the Change of Glabellar Lines (GL)

Phase 1
Recruiting
Conditions
Glabellar Lines
Interventions
First Posted Date
2025-02-19
Last Posted Date
2025-05-07
Lead Sponsor
AbbVie
Target Recruit Count
126
Registration Number
NCT06834789
Locations
🇺🇸

Investigate MD /ID# 270771, Scottsdale, Arizona, United States

🇺🇸

Marcus Facial Plastic Surgery /ID# 270770, Redondo Beach, California, United States

🇺🇸

Skin Research Institute LLC /ID# 270831, Coral Gables, Florida, United States

and more 5 locations

A Study to Evaluate AGN-151586 Intramuscular Injections in Adult Participants for Treatment of Glabellar Lines

Phase 3
Completed
Conditions
Glabellar Lines
Interventions
Drug: Placebo
First Posted Date
2024-03-13
Last Posted Date
2025-03-19
Lead Sponsor
AbbVie
Target Recruit Count
161
Registration Number
NCT06308198
Locations
🇨🇳

Beijing Hospital /ID# 256084, Beijing, Beijing, China

🇯🇵

Tokyo Center Clinic /ID# 267380, Chuo-ku, Tokyo, Japan

🇨🇳

Dermatology Hospital of Southern Medical University /ID# 256172, Guangzhou, Guangdong, China

and more 9 locations

Study of AGN-151586 in Japanese Participants With Moderate to Severe Glabellar Lines

Phase 1
Completed
Conditions
Moderate to Severe Glabellar Lines
Interventions
Drug: Placebo
First Posted Date
2023-11-30
Last Posted Date
2024-04-04
Lead Sponsor
AbbVie
Target Recruit Count
24
Registration Number
NCT06151561
Locations
🇯🇵

Tokyo Center Clinic /ID# 257898, Central District, Tokyo, Japan

A Study to Evaluate Sequential Administration of AGN-151586 and OnabotulinumtoxinA (BOTOX) Injections in Adult Participants for Treatment of Glabellar Lines

Phase 1
Completed
Conditions
Glabellar Lines
Interventions
First Posted Date
2022-08-11
Last Posted Date
2023-06-08
Lead Sponsor
AbbVie
Target Recruit Count
90
Registration Number
NCT05496335
Locations
🇺🇸

The Eye Research Foundation /ID# 244430, Newport Beach, California, United States

🇺🇸

DeNova Research /ID# 244421, Chicago, Illinois, United States

🇺🇸

Bellaire Dermatology Associates /ID# 244428, Bellaire, Texas, United States

and more 7 locations

A Study to Assess Adverse Events of Intramuscular AGN-151586 Injection in Adult Participants With Glabellar Lines

Phase 3
Completed
Conditions
Glabellar Lines
Interventions
First Posted Date
2022-02-21
Last Posted Date
2024-05-29
Lead Sponsor
AbbVie
Target Recruit Count
986
Registration Number
NCT05248893
Locations
🇺🇸

Perelman Center for Advanced Medicine - /ID# 243966, Philadelphia, Pennsylvania, United States

🇺🇸

Northwest Dermatology Institute /ID# 233498, Portland, Oregon, United States

🇺🇸

Swinyer-Woseth Dermatology /ID# 241250, Salt Lake City, Utah, United States

and more 40 locations

A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Toxin-Naïve Adult Participants With Glabellar Lines

Phase 3
Completed
Conditions
Glabellar Lines
Interventions
Drug: Placebo
First Posted Date
2022-02-21
Last Posted Date
2024-01-10
Lead Sponsor
Allergan
Target Recruit Count
309
Registration Number
NCT05248880
Locations
🇨🇦

YVR Aesthetics Training & Study Centre /ID# 241858, Vancouver, British Columbia, Canada

🇺🇸

Delricht Research - 10154 Jefferson /ID# 244890, Baton Rouge, Louisiana, United States

🇺🇸

DMR Research PLLC /ID# 239061, Westport, Connecticut, United States

and more 14 locations

A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Adult Participants With Glabellar Lines

Phase 3
Completed
Conditions
Glabellar Lines
Interventions
Drug: Placebo
First Posted Date
2022-02-21
Last Posted Date
2024-05-24
Lead Sponsor
AbbVie
Target Recruit Count
638
Registration Number
NCT05248867
Locations
🇺🇸

Clinical Testing of Beverly Hills /ID# 233195, Encino, California, United States

🇺🇸

Westside Aesthetics /ID# 232443, Los Angeles, California, United States

🇺🇸

Steven Fagien MD Aesthetic Eyelid Plastic Surgery /ID# 232439, Boca Raton, Florida, United States

and more 35 locations

AGN-151586 Dose-Ranging Study for Treatment of Glabellar Lines

Phase 2
Completed
Conditions
Glabellar Lines
Interventions
Drug: Placebo
First Posted Date
2019-09-19
Last Posted Date
2023-07-28
Lead Sponsor
Allergan
Target Recruit Count
198
Registration Number
NCT04096326
Locations
🇺🇸

DermResearch Inc. /ID# 234483, Austin, Texas, United States

🇺🇸

Austin Institute for Clinical Research /ID# 237135, Pflugerville, Texas, United States

🇺🇸

Center for Dermatology Clinical Research /ID# 237798, Fremont, California, United States

and more 6 locations
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