Clotrimazole
- Generic Name
- Clotrimazole
- Brand Names
- Alevazol, Dermacinrx Therazole Pak, Lotriderm, Lotrimin, Lotrimin AF, Lotrisone, Mycelex
- Drug Type
- Small Molecule
- Chemical Formula
- C22H17ClN2
- CAS Number
- 23593-75-1
- Unique Ingredient Identifier
- G07GZ97H65
- Background
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly di...
- Indication
Topical preparations
Clotrimazole topical cream is indicated for the topical treatment of the following dermal infections , :
Tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum
Candidiasis due to Candida albicans
Tinea versicolor due to Malassezia furfur
...
- Associated Conditions
- Balanitis candida, Candidiasis, Dermatitis, Erythrasma, Fungal Vaginal Infections, Fungal ear infection, Fungal skin infection, Genital candidiasis, Inflammation, Mixed Vaginal Infections, Oropharyngeal Candidiasis, Pityriasis versicolor, Pyoderma, Ringworm, Skin Infections, Skin candida, Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea inguinalis, Trichophytosis, Vaginal Candidiasis, Vaginal Mycosis, Vulvitis, Cutaneous candidiasis, Infection mycotic, Susceptible Bacterial Infections, Symptomatic Tinea Corporis caused by Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum, Symptomatic Tinea Cruris caused by Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum, Symptomatic Tinea Pedis caused by Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum, Tinea versicolor caused by Malassezia infection
- Associated Therapies
- -
A Protocol for the Role of Fractional CO2 Laser in Consolidation Treatment of Recurrent Vulvovaginal Candidiasis
- Conditions
- Interventions
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2020-03-11
- Target Recruit Count
- 205
- Registration Number
- NCT04292704
- Locations
- 🇨🇳
Department of Gynecology of Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Effects of Antimicrobials on the Altered Skin Flora in Arsenical Keratosis
- Conditions
- Interventions
- First Posted Date
- 2018-08-15
- Last Posted Date
- 2018-08-17
- Target Recruit Count
- 30
- Registration Number
- NCT03632733
- Locations
- 🇧🇩
Eruain Community Clinic, Laksham, Bangladesh
ProF-001_Phase IIa
- Conditions
- Interventions
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2019-03-14
- Lead Sponsor
- ProFem GmbH
- Target Recruit Count
- 84
- Registration Number
- NCT03115073
- Locations
- 🇦🇹
Medical University Innsbruck, Innsbruck, Austria
🇦🇹Bezirkskrankenhaus Schwaz, Schwaz, Austria
🇦🇹Medical University Vienna, Vienna, Austria
Patients With Vulvovaginal Candidiasis
- Conditions
- Interventions
- First Posted Date
- 2017-01-18
- Last Posted Date
- 2018-10-19
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 90
- Registration Number
- NCT03024502
- Locations
- 🇧🇷
Clinical Hospital of Sao Paulo University, Ribeirao Preto, Sao Paulo, Brazil
Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.
- First Posted Date
- 2016-12-29
- Last Posted Date
- 2020-06-09
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT03005353
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)
- Conditions
- Interventions
- First Posted Date
- 2016-07-28
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- International Partnership for Microbicides, Inc.
- Target Recruit Count
- 36
- Registration Number
- NCT02847286
Efficacy and Safety of the Association of Clotrimazole and Metronidazole in the Treatment of Vaginal Discharge From Different Etiologies.
- Conditions
- Interventions
- First Posted Date
- 2016-03-18
- Last Posted Date
- 2016-03-18
- Lead Sponsor
- Ache Laboratorios Farmaceuticos S.A.
- Registration Number
- NCT02713139
Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of Otomycosis
- First Posted Date
- 2013-11-25
- Last Posted Date
- 2017-04-04
- Lead Sponsor
- Salvat
- Target Recruit Count
- 190
- Registration Number
- NCT01993823
- Locations
- 🇪🇸
Laboratorios SALVAT, S.A., Esplugues de Llobregat, Barcelona, Spain
Effectiveness of 3% Boric Acid in 70% Alcohol Versus 1% Clotrimazole Solution in Otomycosis Patients
- First Posted Date
- 2012-03-07
- Last Posted Date
- 2015-04-28
- Lead Sponsor
- Khon Kaen Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT01547221
- Locations
- 🇹🇭
ENT clinic KhonKaen Hospital, KhonKaen, Thailand
Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections
- Conditions
- Interventions
- First Posted Date
- 2010-04-16
- Last Posted Date
- 2012-04-12
- Lead Sponsor
- Laboratório Teuto Brasileiro S/A
- Target Recruit Count
- 90
- Registration Number
- NCT01105013
- Locations
- 🇧🇷
Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil
Drug Development Updates
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