Colistin
- Generic Name
- Colistin
- Brand Names
- Cortisporin-TC
- Drug Type
- Small Molecule
- Chemical Formula
- C52H98N16O13
- CAS Number
- 1066-17-7
- Unique Ingredient Identifier
- Z67X93HJG1
- Background
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
- Indication
For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.
- Associated Conditions
- Ear infection bacterial, External ear infection NOS
Tracheobronchitis Prevention Trial
- Conditions
- TracheobronchitisPneumonia
- Interventions
- Other: inhaled normal saline
- First Posted Date
- 2009-12-04
- Last Posted Date
- 2013-06-03
- Lead Sponsor
- University of Thessaly
- Target Recruit Count
- 84
- Registration Number
- NCT01025921
- Locations
- 🇬🇷
University Hospital of Larissa, Larissa, Greece
Nebulized Colistin for Hospital-Acquired Pneumonia
- First Posted Date
- 2009-06-15
- Last Posted Date
- 2009-06-15
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 140
- Registration Number
- NCT00920270
- Locations
- 🇹🇭
Siriraj Hospital, Bangkok, Thailand
Intravenous Colistin Versus Intravenous Colistin Plus Nebulized Colistin in VAP Due MDR Acinetobacter Baumannii
- Conditions
- Cross InfectionPneumonia, Bacterial
- Interventions
- First Posted Date
- 2008-03-28
- Last Posted Date
- 2009-08-06
- Lead Sponsor
- Hospitales Universitarios Virgen del Rocío
- Target Recruit Count
- 67
- Registration Number
- NCT00645723
- Locations
- 🇪🇸
Hospital Universitario Virgen del Rocío, Seville, Spain
Efficacy and Safety of Colistin for Therapy of Infections Caused by ESBL Producing K.Pneumoniae or E.Coli
- Conditions
- Infections
- First Posted Date
- 2006-03-09
- Last Posted Date
- 2006-05-22
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 152
- Registration Number
- NCT00300560
- Locations
- 🇹🇭
Division of Infectious disease and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Bangkoknoi, Bangkok, Thailand
Drug Development Updates
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