MedPath

DC-806

Generic Name
DC-806

A Study to Assess S011806 (DC-806 or LY4100504) in Healthy Adult Participants and Participants With Chronic Plaque Psoriasis

Phase 1
Completed
Conditions
Plaque Psoriasis
Interventions
Other: Placebo
First Posted Date
2025-02-05
Last Posted Date
2025-02-05
Lead Sponsor
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Target Recruit Count
104
Registration Number
NCT06808815
Locations
🇬🇧

The Medicines Evaluation Unit (MEU) Ltd., Manchester, United Kingdom

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2023-10-23
Last Posted Date
2024-01-11
Lead Sponsor
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Target Recruit Count
28
Registration Number
NCT06092931
Locations
🇺🇸

ICON Phase 1 Clinic, Salt Lake City, Utah, United States

Mass Balance and Pharmacokinetics (PK) of [14C]-DC-806 in Healthy Male Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2023-09-21
Last Posted Date
2025-05-04
Lead Sponsor
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Target Recruit Count
8
Registration Number
NCT06045000
Locations
🇳🇱

ICON Phase 1 Clinic, Groningen, Netherlands

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2023-08-16
Last Posted Date
2023-10-04
Lead Sponsor
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Target Recruit Count
33
Registration Number
NCT05994807
Locations
🇺🇸

ICON Phase I Clinic, Salt Lake City, Utah, United States

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

Phase 2
Completed
Conditions
Plaque Psoriasis
Interventions
Other: Placebo
First Posted Date
2023-06-09
Last Posted Date
2025-04-04
Lead Sponsor
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Target Recruit Count
229
Registration Number
NCT05896527
Locations
🇺🇸

First OC Dermatology, Fountain Valley, California, United States

🇨🇦

Lynderm Research Inc. - Probity - PPDS, Markham, Ontario, Canada

🇭🇺

MedMare Bt, Veszprém, Hungary

and more 40 locations
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