Fenofibrate
- Generic Name
- Fenofibrate
- Brand Names
- Antara, Cholib, Fenoglide, Fenomax, Lipidil Supra, Lipofen, Tricor, Triglide
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21ClO4
- CAS Number
- 49562-28-9
- Unique Ingredient Identifier
- U202363UOS
- Background
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.
Fenofibrate was granted FDA approval on 31 December 1993.
- Indication
Fenofibrate is indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C, Triglycerides, and Apo B, and to increase HDL-C adults with primary hypercholesterolemia or mixed dyslipidemia. Fenofibrate is also indicated to treat adults with severe hypertriglyceridemia.
- Associated Conditions
- Mixed Dyslipidemias, Primary Hypercholesterolemia, Severe Hypertriglyceridemia (sHTG), Severe Fredrickson Type IV Hypertriglyceridemia, Severe Fredrickson Type V Hypertriglyceridemia
- Associated Therapies
- -
Extended Release Niacin and Fenofibrate for the Treatment of Atherogenic Dyslipidemia in Obese Females
- First Posted Date
- 2018-08-06
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Lewai Sharki Abdulaziz, MSc PhD
- Target Recruit Count
- 161
- Registration Number
- NCT03615534
- Locations
- 🇮🇶
Lewai S Abdulaziz, Baghdad, Iraq
🇮🇶Al Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
Fibrates in Pediatric Cholestasis
- First Posted Date
- 2018-07-13
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Hoda A. Atta
- Target Recruit Count
- 50
- Registration Number
- NCT03586674
- Locations
- 🇪🇬
Dr. Yassin Abdel Ghaffar Charity Center For Liver Diseases & Researches, Cairo, Nasr City, Egypt
🇪🇬National liver istitute, Shibīn Al Kawm, Egypt
Evaluation of Fenofibrate on Radiation-induced Skin Injury
- First Posted Date
- 2018-06-15
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Second Affiliated Hospital of Soochow University
- Target Recruit Count
- 30
- Registration Number
- NCT03557983
- Locations
- 🇨🇳
苏州大学, Suzhou, Jiangsu, China
Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease
- First Posted Date
- 2018-05-03
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 10
- Registration Number
- NCT03515213
- Locations
- 🇺🇸
University of California, Irvine, Irvine, California, United States
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia
- Conditions
- Interventions
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 153
- Registration Number
- NCT03510884
- Locations
- 🇪🇸
Investigational Site Number :7240003, Pamplona, Navarra, Spain
🇵🇱Investigational Site Number :6160002, Gdansk, Pomorskie, Poland
🇲🇽Investigational Site Number :4840007, Oaxaca, Mexico
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2020-12-29
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 18
- Registration Number
- NCT03510715
- Locations
- 🇩🇰
Investigational Site Number 2080001, Viborg, Denmark
🇪🇸Investigational Site Number 7240001, A Coruna, Spain
🇸🇮Investigational Site Number 7050001, Ljubljana, Slovenia
Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment
- Conditions
- Interventions
- First Posted Date
- 2017-01-05
- Last Posted Date
- 2022-10-28
- Lead Sponsor
- Kowa Research Institute, Inc.
- Target Recruit Count
- 471
- Registration Number
- NCT03011450
- Locations
- 🇺🇸
South Florida Research Solutions LLC., Pembroke Pines, Florida, United States
🇺🇸Boyett Health Services Inc, Hamilton, Alabama, United States
🇺🇸Longwood Research - Saadat Ansari, MD, LLC, Huntsville, Alabama, United States
Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function
- Conditions
- Interventions
- First Posted Date
- 2016-12-23
- Last Posted Date
- 2022-11-30
- Lead Sponsor
- Kowa Research Institute, Inc.
- Target Recruit Count
- 551
- Registration Number
- NCT03001817
- Locations
- 🇺🇸
Maryland Cardiovascular Specialist, Baltimore, Maryland, United States
🇺🇸Protenium Clinical Research, LLC - Dallas, Dallas, Texas, United States
🇺🇸Centex Studies, Inc., Houston, Texas, United States
Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia
- First Posted Date
- 2016-12-07
- Last Posted Date
- 2019-09-09
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 206
- Registration Number
- NCT02984982
- Locations
- 🇯🇵
Investigational Site Number 392008, Gifu-shi, Japan
🇯🇵Investigational Site Number 392022, Chiyoda-ku, Japan
🇯🇵Investigational Site Number 392039, Hiroshima-shi, Japan
Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCA
- First Posted Date
- 2016-11-17
- Last Posted Date
- 2021-09-17
- Lead Sponsor
- Beijing 302 Hospital
- Registration Number
- NCT02965911
- Locations
- 🇨🇳
Beijing 302 hospital, Beijing, China
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.