Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
hCAP18 Levels and Vitamin D Deficiency in Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2009-12-04
- Last Posted Date
- 2015-09-23
- Lead Sponsor
- Massachusetts General Hospital
- Registration Number
- NCT01026363
- Locations
- 🇺🇸
Massachusetts Institute of Technology, Cambridge, Massachusetts, United States
Study of Vitamin D Supplementation to Male HIV Sero-positive Patients
- Conditions
- Interventions
- First Posted Date
- 2009-10-07
- Last Posted Date
- 2012-09-17
- Lead Sponsor
- Hvidovre University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT00990678
- Locations
- 🇩🇰
Dept. of endocrinology, Hvidovre Hospital, Copenhagen, Denmark
Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity
- Conditions
- Interventions
- First Posted Date
- 2009-08-06
- Last Posted Date
- 2017-03-07
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 21
- Registration Number
- NCT00953849
- Locations
- 🇺🇸
Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina, United States
Gene Expression Profile of Breast Cancer Samples After Vitamin D Supplementation
- First Posted Date
- 2009-06-23
- Last Posted Date
- 2012-11-01
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT00926315
- Locations
- 🇧🇷
Instituto Brasileiro de Controle do Câncer - IBCC, São Paulo, SP, Brazil
The Pharmacokinetics of Rocaltrol When Administered Alone or in Combination With Fosrenol or Renvela in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2009-06-22
- Last Posted Date
- 2021-06-15
- Lead Sponsor
- Shire
- Target Recruit Count
- 41
- Registration Number
- NCT00925704
- Locations
- 🇺🇸
West Coast Clinical Trials, Cypress, California, United States
Calcitriol, Physical Activity, and Bone Health in Cancer Survivors
- Conditions
- Interventions
- First Posted Date
- 2009-05-19
- Last Posted Date
- 2019-04-23
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 41
- Registration Number
- NCT00904033
- Locations
- 🇺🇸
University of Rochester Medical Center, Rochester, New York, United States
Calcitriol in the Treatment of Immunoglobulin A Nephropathy
- First Posted Date
- 2009-03-17
- Last Posted Date
- 2011-02-17
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT00862693
- Locations
- 🇨🇳
Renal Division, Peking University First Hospital, Beijing, Beijing, China
Paricalcitol Versus Calcitriol for Efficacy and Safety in Stage 3/4 Chronic Kidney Disease (CKD) With Secondary Hyperparathyroidism (SHPT)
- Conditions
- Interventions
- First Posted Date
- 2009-01-15
- Last Posted Date
- 2014-08-07
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 110
- Registration Number
- NCT00823303
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Northshore University Health System, Evanston, Illinois, United States
🇺🇸Washington University, St. Louis, Missouri, United States
Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism
- Conditions
- Interventions
- First Posted Date
- 2008-12-02
- Last Posted Date
- 2012-12-06
- Lead Sponsor
- Penang Hospital, Malaysia
- Target Recruit Count
- 69
- Registration Number
- NCT00800358
- Locations
- 🇲🇾
Hospital Sultanah Bahiyah Haemodialysis Unit KM 6 Jalan Langgar, Alor Star, Kedah, Malaysia
🇲🇾Clinical Research Centre, Penang Hospital, Georgetown, Penang, Malaysia
🇲🇾Nephrology Department, Tengku Ampuan Rahimah Hospital, Klang, Selangor, Malaysia
Phase I/II Calcitriol in Lung Cancer
- First Posted Date
- 2008-11-20
- Last Posted Date
- 2017-12-12
- Lead Sponsor
- University of Michigan Rogel Cancer Center
- Target Recruit Count
- 34
- Registration Number
- NCT00794547
- Locations
- 🇺🇸
St. Joseph Mercy Hospital, Ann Arbor, Michigan, United States
🇺🇸Roswell Park Cancer Institute, Buffalo, New York, United States
🇺🇸University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Drug Development Updates
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