Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 199...
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also ...
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Methadone vs Magnesium in Spinal Fusion
- Conditions
- Interventions
- First Posted Date
- 2013-02-20
- Last Posted Date
- 2018-02-08
- Lead Sponsor
- Nationwide Children's Hospital
- Target Recruit Count
- 63
- Registration Number
- NCT01795495
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
Intrathecal Magnesium for Same-day-surgery
- Conditions
- Interventions
- First Posted Date
- 2013-02-18
- Last Posted Date
- 2014-03-10
- Lead Sponsor
- Hospital General de Ciudad Real
- Target Recruit Count
- 21
- Registration Number
- NCT01794247
- Locations
- 🇪🇸
Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
🇪🇸Hospital General universitario de Ciudad Real, Ciudad Real, Castilla-La Mancha, Spain
Magnesium Sulphate and Sevoflurane Induced Emergence Agitation in Children
- Conditions
- Interventions
- First Posted Date
- 2012-12-06
- Last Posted Date
- 2013-02-15
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 70
- Registration Number
- NCT01743144
- Locations
- 🇪🇬
Anesthesia department - Faculty of medicine- Cairo University, Cairo, Egypt
Efficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic Encephalopathy
- Conditions
- Interventions
- First Posted Date
- 2012-07-20
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- Sajjad Rahman
- Target Recruit Count
- 300
- Registration Number
- NCT01646619
- Locations
- 🇦🇪
Tawam Hospital, AlAin, United Arab Emirates
🇶🇦NICU,Women's Hospital, Hamad Medical Corporation, Doha, Qatar
🇲🇾University Malaya Medical Center (UMMC), Kuala Lumpur, Malaysia
Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients
- Conditions
- Interventions
- First Posted Date
- 2012-05-18
- Last Posted Date
- 2018-01-17
- Lead Sponsor
- Sara Varea
- Target Recruit Count
- 55
- Registration Number
- NCT01601314
- Locations
- 🇪🇸
Hospital Clinic of Barcelona, Barcelona, Spain
Intravenous Magnesium Infusion in Patients Undergoing Cardioversion of Atrial Fibrillation Trial
- Conditions
- Interventions
- First Posted Date
- 2012-05-14
- Last Posted Date
- 2020-10-22
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 261
- Registration Number
- NCT01597557
- Locations
- 🇺🇸
State University of New York at Buffalo, Buffalo, New York, United States
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma
- First Posted Date
- 2012-04-25
- Last Posted Date
- 2014-01-28
- Lead Sponsor
- Hamad Medical Corporation
- Target Recruit Count
- 400
- Registration Number
- NCT01584726
- Locations
- 🇶🇦
Pediatric Emergency Centre, Doha, Qatar
🇶🇦Hamad Medical Corporation, Doha, Qatar
Pilot Study of Magnesium Infusions in Pediatric Asthma
- First Posted Date
- 2012-01-31
- Last Posted Date
- 2017-03-30
- Lead Sponsor
- University of Louisville
- Registration Number
- NCT01522040
- Locations
- 🇺🇸
Kosair Children's Hospital, Louisville, Kentucky, United States
Intra-arterial Magnesium Administration for Acute Stroke
- First Posted Date
- 2012-01-02
- Last Posted Date
- 2017-08-28
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 4
- Registration Number
- NCT01502761
- Locations
- 🇺🇸
University California Los Angeles: Ronald Reagan and Santa Monica Hospitals, Los Angeles, California, United States
🇺🇸University of Southern California University and LA County Hospitals, Los Angeles, California, United States
Magnesium Sulphate for Preterm Birth (MASP Study)
- First Posted Date
- 2011-12-15
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Hvidovre University Hospital
- Target Recruit Count
- 560
- Registration Number
- NCT01492608
- Locations
- 🇩🇰
Gynækologisk afdeling D, Odense, Fyn, Denmark
🇩🇰Gynækologisk obstetrisk afdeling, Randers, Jylland, Denmark
🇩🇰Hanne Trap Wolf, Hvidovre, Danmark, Denmark
Drug Development Updates
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