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NC-410

Generic Name
NC-410

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

First Posted Date
2025-04-24
Last Posted Date
2025-04-24
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
20
Registration Number
NCT06941857
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors

Phase 1
Active, not recruiting
Conditions
Ovarian Cancer
Colo-rectal Cancer
Advanced or Metastatic Solid Tumors
Lung Cancer
Microsatellite Instability High
Microsatellite Stable
Endometrial Cancer
Cervical Cancer
Esophageal Cancer
Microsatellite Instability Low
Interventions
First Posted Date
2022-10-10
Last Posted Date
2024-12-16
Lead Sponsor
NextCure, Inc.
Target Recruit Count
97
Registration Number
NCT05572684
Locations
🇺🇸

Arizona Oncology Associates, Tucson, Arizona, United States

🇺🇸

Rocky Mountain Cancer Centers, Aurora, Colorado, United States

🇺🇸

St. Elizabeth Edgewood Hospital, Edgewood, Kentucky, United States

and more 14 locations

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

Phase 1
Terminated
Conditions
Ovarian Cancer
Gastric Cancer
Colo-rectal Cancer
Advanced or Metastatic Solid Tumors
Interventions
First Posted Date
2020-05-29
Last Posted Date
2024-07-25
Lead Sponsor
NextCure, Inc.
Target Recruit Count
46
Registration Number
NCT04408599
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

🇺🇸

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

NIH National Cancer Institute (NCI), Bethesda, Maryland, United States

and more 2 locations
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