Frovatriptan

Generic Name
Frovatriptan
Brand Names
Frova
Drug Type
Small Molecule
Chemical Formula
C14H17N3O
CAS Number
158747-02-5
Unique Ingredient Identifier
H82Q2D5WA7
Background

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.

Indication

For the acute treatment of migraine attacks with or without aura in adults.

Associated Conditions
Migraine With Aura, Migraine Without Aura, Migraine;Menstrual
Associated Therapies
-

Frovatriptan as a Transitional Therapy in Medication Overuse Headache

First Posted Date
2010-01-07
Last Posted Date
2019-04-18
Lead Sponsor
University of Calgary
Target Recruit Count
55
Registration Number
NCT01044251
Locations
🇨🇦

South Health Campus, Calgary, Alberta, Canada

Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine

First Posted Date
2009-05-19
Last Posted Date
2010-02-15
Lead Sponsor
Endo Pharmaceuticals
Target Recruit Count
192
Registration Number
NCT00904098

Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-02-18
Last Posted Date
2012-01-13
Lead Sponsor
Clinvest
Target Recruit Count
55
Registration Number
NCT00846495
Locations
🇺🇸

Physician Associates LLC, Oviedo, Florida, United States

🇺🇸

Clinvest, Springfield, Missouri, United States

A Double Blind Placebo-controlled, Parallel Group Study to Assess the Efficacy and Safety of Frovatriptan in the Acute Treatment of Migraine

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-01-13
Last Posted Date
2013-04-18
Lead Sponsor
SK Chemicals Co., Ltd.
Target Recruit Count
298
Registration Number
NCT00821483

Prevention of Menstrual Migraines: Using Frovatriptan or Placebo During Hormone Free Intervals

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-06-18
Last Posted Date
2011-07-25
Lead Sponsor
Scott and White Hospital & Clinic
Target Recruit Count
30
Registration Number
NCT00700128
Locations
🇺🇸

Scott & White Memorial Hospital, Temple, Texas, United States

A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine

First Posted Date
2008-03-26
Last Posted Date
2024-01-02
Lead Sponsor
Endo Pharmaceuticals
Target Recruit Count
579
Registration Number
NCT00644033
Locations
🇺🇸

Endo Pharmaceuticals, Chadds Ford, Pennsylvania, United States

A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2007-02-26
Last Posted Date
2011-05-26
Lead Sponsor
Thomas Jefferson University
Target Recruit Count
74
Registration Number
NCT00440232
Locations
🇺🇸

Jefferson Headache Center, Philadelphia, Pennsylvania, United States

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