Remimazolam
- Generic Name
- Remimazolam
- Brand Names
- Byfavo
- Drug Type
- Small Molecule
- Chemical Formula
- C21H19BrN4O2
- CAS Number
- 308242-62-8
- Unique Ingredient Identifier
- 7V4A8U16MB
- Background
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid biotransformation and elimination as inactive metabolites. These "soft drugs" are useful in the context of surgical procedures, wherein a rapid onset/offset is desirable, enabling anesthesiologists to manipulate drug concentrations as needed. Remimazolam was the first "soft" benzodiazepine analog to be developed and was approved for use by the FDA in July 2020 under the brand name Byfavo.
- Indication
Remimazolam is indicated for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 minutes or less.
- Associated Conditions
- Procedural Sedation
- Associated Therapies
- -
The Effects of Remimazolam on the Incidence of Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
- Conditions
- HypoxiaHysteroscopyOverweight or Obesity
- Interventions
- First Posted Date
- 2023-08-22
- Last Posted Date
- 2023-08-28
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 600
- Registration Number
- NCT06004843
- Locations
- 🇨🇳
Renji Hospital, Shanghai, Pudong New Area, China
Dose of Remi in Children
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2023-08-14
- Lead Sponsor
- Zhihong LU
- Target Recruit Count
- 25
- Registration Number
- NCT05990673
Remimazolam for Cataract Surgery
- Conditions
- Cataract SurgeryCognitive Impairment
- Interventions
- First Posted Date
- 2023-08-07
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- University of California, Los Angeles
- Target Recruit Count
- 120
- Registration Number
- NCT05980117
- Locations
- 🇺🇸
Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California, United States
The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia
- Conditions
- Spinal AnesthesiaRemimazolam
- Interventions
- First Posted Date
- 2023-07-07
- Last Posted Date
- 2023-08-08
- Lead Sponsor
- Pusan National University Yangsan Hospital
- Target Recruit Count
- 72
- Registration Number
- NCT05935657
Effect of Sevoflurane and Remimazolam on Arterial Oxygenation During One-lung Ventilation
- Conditions
- RemimazolamOne-Lung VentilationThoracic Surgery, Video-Assisted
- Interventions
- First Posted Date
- 2023-06-18
- Last Posted Date
- 2024-08-12
- Lead Sponsor
- Pusan National University Yangsan Hospital
- Target Recruit Count
- 66
- Registration Number
- NCT05907525
- Locations
- 🇰🇷
Pusan National University Yangsan Hospital, Yangsan, Please Select, Korea, Republic of
Remimazolam for Postoperative Atrial Fibrillation
- Conditions
- RemimazolamCoronary Artery Bypass Grafting
- Interventions
- First Posted Date
- 2023-06-06
- Last Posted Date
- 2023-06-06
- Lead Sponsor
- Yangzhou University
- Target Recruit Count
- 50
- Registration Number
- NCT05891145
- Locations
- 🇨🇳
The Affiliated Hospital of Yangzhou University., Yangzhou, Jiangsu, China
The Effect of Remimazolam on Opioid Induced Hyperalgesia
- Conditions
- Hyperalgesia, Mechanical
- Interventions
- First Posted Date
- 2023-05-19
- Last Posted Date
- 2023-10-06
- Lead Sponsor
- Wonkwang University Hospital
- Target Recruit Count
- 108
- Registration Number
- NCT05866315
- Locations
- 🇰🇷
Wonkwag UH, Iksan, Jeollabukdo, Korea, Republic of
🇰🇷Wonkwang University hospital, Iksan, Korea, Republic of
Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
- First Posted Date
- 2023-05-01
- Last Posted Date
- 2023-05-01
- Lead Sponsor
- Samsung Medical Center
- Target Recruit Count
- 132
- Registration Number
- NCT05836545
- Locations
- 🇰🇷
Samsung Medical Center, Seoul, Korea, Republic of
Continuous Infusion of Remidazolam for Colonoscopic Polypectomy in Elderly Patients
- First Posted Date
- 2023-04-06
- Last Posted Date
- 2024-08-13
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 114
- Registration Number
- NCT05801757
- Locations
- 🇨🇳
Tongji Hospital, Wuhan, Hubei, China
Comparative Study of Recovery Characteristics Between Remimazolam Anesthesia With Flumazenil and Desflurane Anesthesia for Closed Reduction of Nasal Bone Fracture
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- Daegu Catholic University Medical Center
- Target Recruit Count
- 58
- Registration Number
- NCT05774366
- Locations
- 🇰🇷
Daegu Catholic University Medical Center, Daegu, Korea, Republic of
Drug Development Updates
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