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Natamycin

Generic Name
Natamycin
Brand Names
Natacyn
Drug Type
Small Molecule
Chemical Formula
C33H47NO13
CAS Number
7681-93-8
Unique Ingredient Identifier
8O0C852CPO
Background

Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]

Indication

For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.

Associated Conditions
Fungal blepharitis, Fungal conjunctivitis, Fungal infections of the cornea
Associated Therapies
-

Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction

Phase 3
Active, not recruiting
Conditions
Acanthamoeba Keratitis
Fungal Keratitis
Interventions
First Posted Date
2021-11-05
Last Posted Date
2024-07-19
Lead Sponsor
University of California, San Francisco
Target Recruit Count
330
Registration Number
NCT05110001
Locations
🇮🇳

Aravind Eye Care System, Madurai, Tamil Nadu, India

🇧🇷

Federal University of São Paulo, São Paulo, Brazil

Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers

Phase 3
Completed
Conditions
Fungal Keratitis
Corneal Ulcer
Interventions
First Posted Date
2016-04-07
Last Posted Date
2019-10-01
Lead Sponsor
University of California, San Francisco
Target Recruit Count
70
Registration Number
NCT02731638
Locations
🇮🇳

Aravind Eye Hospitals, Pondicherry, Tamil Nadu, India

🇺🇸

Francis I. Proctor Foundation at UCSF, San Francisco, California, United States

Mycotic Ulcer Treatment Trial I

Phase 3
Completed
Conditions
Eye Infections, Fungal
Corneal Ulcer
Interventions
First Posted Date
2009-10-16
Last Posted Date
2018-08-01
Lead Sponsor
University of California, San Francisco
Target Recruit Count
323
Registration Number
NCT00996736
Locations
🇮🇳

Aravind Eye Hospital, Pondicherry, Tamil Nadu, India

🇮🇳

Aravind Eye Hospitals, Madurai, Tamil Nadu, India

🇺🇸

Proctor Foundation, UCSF, San Francisco, California, United States

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