Ceftazidime
- Generic Name
- Ceftazidime
- Brand Names
- Avycaz, Fortaz, Tazicef, Zavicefta
- Drug Type
- Small Molecule
- Chemical Formula
- C22H22N6O7S2
- CAS Number
- 72558-82-8
- Unique Ingredient Identifier
- DZR1ENT301
- Background
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall...
- Indication
Ceftazidime is indicated for the treatment of lower respiratory tract infections, skin and skin structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections, intra-abdominal infections (including peritonitis), and central nervous system infections (including meningitis) caused by susceptible bacteria...
- Associated Conditions
- Bacteremia, Bacterial Infections, Bacterial Septicemia, Bone and Joint Infections, Bronchopulmonary Infection, Central Nervous System Infections, Complicated Intra-Abdominal Infections (cIAIs), Complicated Skin and Soft Tissue Infection, Complicated Urinary Tract Infection, Complicated Urinary Tract Infections caused by susceptible Gram-negative microorganisms, Fever caused by susceptible bacteria, Gynecological Infection, Intraabdominal Infections, Lower Respiratory Tract Infection (LRTI), Meningitis, Bacterial, Nosocomial Pneumonia, Peritoneal Dialysis Associated Peritonitis, Skin and skin structure infections, Urinary Tract Infection, Ventilator-associated Bacterial Pneumonia caused by susceptible Gram-negative microorganisms, Chronic suppurative Otitis media, Hospital-acquired bacterial pneumonia caused by susceptible Gram-negative microorganisms, Malignant Otitis Externa, Susceptible Intra-Abdominal Infection caused by susceptible Gram-negative microorganism
- Associated Therapies
- -
Is Cefazolin, Ceftazidime and Ciprofloxacin Dosing Optimal in Hemodialysis Patients?
- Conditions
- Interventions
- First Posted Date
- 2020-03-24
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- University of Manitoba
- Target Recruit Count
- 40
- Registration Number
- NCT04319328
- Locations
- 🇨🇦
College of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
🇨🇦Saint Boniface Hospital, Outpatient Hemodialysis Unit, Winnipeg, Manitoba, Canada
Antibiotic Therapy vs Laparscopic Appendectomy in Pediatric Chronic Appendicitis
- First Posted Date
- 2018-11-27
- Last Posted Date
- 2018-11-28
- Lead Sponsor
- Zunyi Medical College
- Target Recruit Count
- 200
- Registration Number
- NCT03754387
- Locations
- 🇨🇳
children's hospital of Guiyang, Guiyang, Guizhou, China
🇨🇳Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China
🇨🇳The first people hospital of zunyi, Zunyi, Guizhou, China
Single- Versus Multiple-dose Antimicrobial Prophylaxis for The Prevention of Infectious Complications Associated With Peroral Endoscopic Myotomy(POEM) for Achalasia
- First Posted Date
- 2018-01-19
- Last Posted Date
- 2018-11-07
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 666
- Registration Number
- NCT03404739
- Locations
- 🇨🇳
Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741
- Conditions
- Interventions
- First Posted Date
- 2017-12-18
- Last Posted Date
- 2018-01-05
- Lead Sponsor
- Spero Therapeutics
- Target Recruit Count
- 27
- Registration Number
- NCT03376529
- Locations
- 🇬🇧
Simbec Research, Ltd., Merthyr Tydfil,, Mid Glamorgan, United Kingdom
LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients
- Conditions
- Interventions
- First Posted Date
- 2016-07-21
- Last Posted Date
- 2021-12-15
- Lead Sponsor
- University Ghent
- Target Recruit Count
- 40
- Registration Number
- NCT02840136
- Locations
- 🇧🇪
Ghent University, Ghent, Oost-Vlaanderen, Belgium
Lung Concentrations of Ceftazidime in Patients With Ventilator-associated Pneumonia
- First Posted Date
- 2016-07-20
- Last Posted Date
- 2016-07-20
- Lead Sponsor
- CHU de Reims
- Target Recruit Count
- 34
- Registration Number
- NCT02837835
- Locations
- 🇫🇷
Chu Reims, France, Reims, France
Vancomycin Plus Moxifloxacin Versus Vancomycin Plus Ceftazidime for the Treatment of Peritoneal Dialysis (PD)-Related Peritonitis
- Conditions
- Interventions
- First Posted Date
- 2016-06-01
- Last Posted Date
- 2020-03-26
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02787057
Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified
- First Posted Date
- 2015-08-18
- Last Posted Date
- 2022-06-02
- Lead Sponsor
- University College Cork
- Target Recruit Count
- 223
- Registration Number
- NCT02526004
- Locations
- 🇮🇪
University College Cork, Cork, Ireland
Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia
- Conditions
- Interventions
- First Posted Date
- 2015-06-04
- Last Posted Date
- 2015-06-04
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 110
- Registration Number
- NCT02463747
- Locations
- 🇮🇱
Tel-Aviv Sourasky Medicak center / BMT Unit, Tel-Aviv, Israel
Post ERCP Pancreatitis Prevention in Average Risk Patients
- First Posted Date
- 2013-02-05
- Last Posted Date
- 2015-04-08
- Lead Sponsor
- University Hospital Rijeka
- Target Recruit Count
- 124
- Registration Number
- NCT01784445
- Locations
- 🇭🇷
Clinical Hospital Centre, Rijeka, Kresimirova 42, Croatia
Drug Development Updates
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